25391-58-6

Basic information

• Product Name: 2-HYDROXY-3-IODO-5-NITROPYRIDINE 97
• Synonyms: 2-HYDROXY-3-IODO-5-NITROPYRIDINE 97;3-IODO-5-NITROPYRIDIN-2-OL;2(1H)-Pyridinone, 3-iodo-5-nitro-;2-Hydroxy-3-iodo-5-nitropyridine≥ 99% (HPLC)
• CAS NO: 25391-58-6
• Molecular Formula: C₅H₃IN₂O₃
• Molecular Weight: 265.99
• Product Categories: Pyridines;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;alcohol|alkyl Iodine|nitro-compound
• Mol File: 25391-58-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 203-207 °C(lit.)
• Boiling Point: 317.901°C at 760 mmHg
• Flash Point: 146.062°C
• Appearance: /
• Density: 2.279g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.703
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 6.62±0.10(Predicted)
• CAS DataBase Reference: 2-HYDROXY-3-IODO-5-NITROPYRIDINE 97(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXY-3-IODO-5-NITROPYRIDINE 97(25391-58-6)
• EPA Substance Registry System: 2-HYDROXY-3-IODO-5-NITROPYRIDINE 97(25391-58-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22-41
• Safety Statements: 26-39
• WGK Germany: 3
• Hazardous Substances Data: 25391-58-6(Hazardous Substances Data)

Usage

Chemical Properties

Brick red to brown powder

InChI:InChI=1/C5H3IN2O3/c6-4-1-3(8(10)11)2-7-5(4)9/h1-2H,(H,7,9)

Upstream product

• 5418-51-9 5-nitro-2-hydroxypyridine 

Downstream Products

• 25391-60-0 2-chloro-3-iodo-5-nitropyridine 
• 31676-54-7 3-amino-5-phenylpyridine 
• 1119085-63-0 5-methyl-2-(6-phenyl-5-(trifluoromethyl)pyridin-3-ylamino)benzoic acid 
• 1119090-36-6 ethyl 5-cyclopropyl-2-(6-methoxy-5-phenylpyridin-3-ylamino)benzoate 
• 1119085-11-8 5-Cyclopropyl-2-(6-methoxy-5-phenylpyridin-3-ylamino) benzoic acid 
• 1119088-25-3 N-(6-phenyl-5-(trifluoromethyl)pyridin-3-yl)acetamide 
• 1119088-10-6 6-phenyl-5-(trifluoromethyl)pyridin-3-amine 
• 1119088-63-9 2-cyclopropyl-5-nitro-3-phenylpyridine 
• 1119088-60-6 6-cyclopropyl-5-phenylpyridin-3-amine 
• 1119088-38-8 2-bromo-5-nitro-3-phenylpyridine 
• 881209-08-1 6-methoxy-5-phenylpyridin-3-ylamine 
• 99368-68-0 6-chloro-5-(trifluoromethyl)pyridin-3-amine 
• 99368-67-9 2-chloro-5-nitro-3-(trifluoromethyl)pyridine 
• 131941-24-7 5-nitro-2,3-diphenylpyridine 

Relevant articles and documents

PROTEASOME ACTIVITY ENHANCING COMPOUNDS

The present invention is directed to compounds having the Formula (I), (II), (III), (IV), and (V), compositions thereof, the methods of synthesis of the compouds of interest, and to methods for the treatment of a condition associated with a dysfunction in proteostasis, such as cancer, inflammatory conditions, neurodegeneration, metabolic conditions, comprising administering an effective amount of a compound of the invention.

Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function

Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds.