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Trimethylsilyl p-aminobenzoate is an organic compound with the chemical formula C11H17NO2Si. It is a derivative of p-aminobenzoic acid, where the carboxylic acid group is protected by a trimethylsilyl group. This protection is often used in organic synthesis to prevent unwanted reactions at the carboxylic acid site. The compound is a colorless liquid and is soluble in common organic solvents. It is used as a protecting group in the synthesis of various pharmaceuticals and other organic compounds, allowing chemists to control the reactivity of the molecule at different stages of the synthesis process.

25432-40-0

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25432-40-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 25432-40-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,4,3 and 2 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 25432-40:
(7*2)+(6*5)+(5*4)+(4*3)+(3*2)+(2*4)+(1*0)=90
90 % 10 = 0
So 25432-40-0 is a valid CAS Registry Number.

25432-40-0Relevant academic research and scientific papers

A Simple and Versatile Synthesis of Trimethylsiloxy-Substituted Isocyanates

Mormann, Werner,Leukel, Gabriele

, p. 990 - 992 (1988)

A versatile and efficient method for the synthesis of trimethylsiloxy-substituted isocyanates without the use of carbonyl chloride consists of the reaction of the O-trimethylsilyl derivatives of aminoalcohols, aminophenols, 4-aminobenzoic acid, and hydrox

A simple and efficient room temperature silylation of diverse functional groups with hexamethyldisilazane using CeO2 nanoparticles as solid catalysts

Anbu, Nagaraj,Vijayan, Chellappa,Dhakshinamoorthy, Amarajothi

, (2019/06/08)

In this study, a mild and efficient method is developed for the silylation of diverse functional groups using CeO2 nanoparticles (n-CeO2) as solid catalysts with hexamethyldisilazane (HMDS) as silylating agent at room temperature. Alcohols, phenols and acids are silylated to their respective silyl derivatives with faster reaction rate while amines and thiols required relatively longer reaction time. Moreover, the solid catalyst is easily be separated from the reaction mixture and recycled more than five times without any obvious decay in its activity. Powder X-ray diffraction (XRD), transmission electron microscope (TEM), UV–vis diffuse reflectance spectra (UV-DRS) and Raman analyses revealed identical structural integrity, particle size, absorption edge and valence state for the reused solid compared to the fresh solid catalyst.

Process for the preparation of isocyanates and their use for the preparation of polyisocyanates containing ester

-

, (2008/06/13)

This invention relates to a novel process for the preparation of isocyanates containing silylated alcoholic or phenolic hydroxyl groups as substituents and to the use of the compounds obtained by this process as reactants for isocyanatocarboxylic acid halides in the preparation of polyisocyanates containing ester groups.

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