25436-90-2

Usage

InChI:InChI=1/C20H32O2/c1-14(13-18(21)22)9-11-19(4)16(3)10-12-20(5)15(2)7-6-8-17(19)20/h7,13,16-17H,6,8-12H2,1-5H3,(H,21,22)/b14-13+/t16-,17-,19+,20+/m1/s1

Upstream product

• 23527-24-4 kolavenic acid methyl ester 
• 89162-97-0 (R)-(+)-3,4-dimethyl-2-cyclohexen-1-one 
• 112358-88-0 (3R,4S,4aR,8aR)-4-(2-Bromo-ethyl)-3,4,8,8a-tetramethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalene 
• 112420-63-0 (4aR,5S,6R)-5-ethenyl-4,4a,5,6,7,8-hexahydro-1,5,6-trimethyl-2(3H)-naphthalenone 
• 112420-64-1 (1S,2R,4aS,5S,6R,8aR)-6-Hydroxy-1,2,5-trimethyl-1-vinyl-octahydro-naphthalene-4a-carbonitrile 
• 112358-87-9 2,2-Dimethyl-propionic acid 2-((1S,2R,4aS,8aR)-4a-cyano-1,2,5-trimethyl-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl)-ethyl ester 

Relevant academic research and scientific papers

Asymmetric Synthesis of Clerodane Diterpenoids: Total Synthesis of (-)-Methyl Kolavenate

The asymmetric synthesis of (8R,9S,10R)-4,8,9-trimethyl-9-vinyl-Δ4-3-octalone, a versatile intermediate for the syntheses of both trans- and cis-neo-clerodane diterpenoids, has been achieved by extension of Ender's asymmetric alkylation, and its utility is exemplified by the total synthesis of (-)-methyl kolavenate, the first example of a clerodane diterpenoid in optically active form.