25442-39-1Relevant articles and documents
Thiazolidin-5-imine Formation as a Catalyst-Free Bioorthogonal Reaction for Protein and Live Cell Labeling
Bi, Xiaobao,Yin, Juan,Rao, Chang,Balamkundu, Seetharamsing,Banerjee, Biplab,Zhang, Dingpeng,Zhang, Dawei,Dedon, Peter C.,Liu, Chuan-Fa
, p. 7790 - 7793 (2018)
A previously undescribed reaction involving the formation of a thiazolidin-5-imine linkage was developed for bioconjugation. Being highly specific and operating in aqueous media, this simple condensation reaction is used to chemoselectively label peptides, proteins, and living cells under physiological conditions without the need to use toxic catalysts or reducing reagents.
Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs
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Page/Page column 65; 66; 67; 74, (2017/05/17)
The invention relates to prodrugs for use in the inhibition of histone deacetylase. The prodrugs of the present invention have good aqueous solubility and good aqueous stability. The prodrugs of the invention advantageously are metabolized to the active i
Prodrugs of Compounds that Enhance Antifungal Activity and Compositions of Said Prodrugs
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Paragraph 0357; 0358; 0372, (2015/07/27)
The invention relates to prodrugs for use in the inhibition of histone deacetylase. The prodrugs of the present invention have good aqueous solubility and good aqueous stability. The prodrugs of the invention advantageously are metabolized to the active i
ANTIANGIOGENIC DRUG TO TREAT CANCER, ARTHRITIS AND RETINOPATHY
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Page/Page column 11, (2010/11/24)
Compounds having Formula (I) or pharmaceutically acceptable salts or prodrugs thereof, are useful for treating pathological states which arise from or are exacerbated by angiogenesis. The invention also relates to pharmaceutical compositions comprising th