25444-98-8

Basic information

• Product Name: 2(3H)-Oxazolethione, 3-methyl-5-phenyl-
• CAS NO: 25444-98-8
• Molecular Formula: C10H9NOS
• Molecular Weight: 191.254
• Mol File: 25444-98-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2(3H)-Oxazolethione, 3-methyl-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Oxazolethione, 3-methyl-5-phenyl-(25444-98-8)
• EPA Substance Registry System: 2(3H)-Oxazolethione, 3-methyl-5-phenyl-(25444-98-8)

Safety Data

• Hazardous Substances Data: 25444-98-8(Hazardous Substances Data)

Upstream product

• 25444-97-7 2-methylsulfanyl-5-phenyloxazole 
• 74-88-4 methyl iodide 
• 16172-23-9 5-phenyl-3H-oxazole-2-thione 
• 164594-44-9 N-methyl-3-hydroxy-3-phenylazetidine-2-thione 

Downstream Products

• 37052-74-7 2-(3-methyl-5-phenyl-3H-oxazol-2-ylidene)-1-phenyl-ethanone 

Relevant articles and documents

Hydroxy-β-thiolactams to oxazole-2-thiones. A novel dmso-promoted oxidation

(Chemical Equation Presented) 3-Aryl-3-hydroxy-1-methylazetidine-2-thiones react with HCI in DMSO to give 3-methyl-5-aryloxazole-2-thiones. Substituent effects correlate with rate effects on hydrolyses of acetals of benzaldehyde. An 17O labeling experiment indicates that the oxygen atom of the product is derived from the hydroxyl group. Trifluoroacetic anhydride/DMSO in CH2Cl2 can also promote the reaction. Mechanisms involving a Grob-type fragmentation of an activated substrate, followed by recyclization, or a cyclopropylcarbinyl type of rearrangement can account for this oxidative rearrangement.