25449-96-1

Basic information

• Product Name: 3-AMINO-4-METHYLBENZOTRIFLUORIDE
• Synonyms: 2-METHYL-5-(TRIFLUOROMETHYL)ANILINE;BENZENAMINE, 2-METHYL-5-TRIFLUOROMETHYL;2-methyl-5-thifluoromethylaniline;2-methyl-5-trifluoromethylaniline(MTA);2-Methyl-5-Trifluoromethylanil;3-Amino-4-methylbenzotrifluoride 98%;3-Amino-4-methylbenzotrifluoride98%;2-Methy-5-(trifluoroMethyl)aniline
• CAS NO: 25449-96-1
• Molecular Formula: C₈H₈F₃N
• Molecular Weight: 175.15
• Product Categories: Trifluoromethylbenzene serise;Amines;blocks;FluoroCompounds
• Mol File: 25449-96-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 34-38°C
• Boiling Point: 74°C/8mmHg(lit.)
• Flash Point: 96°C
• Appearance: /
• Density: 1.237 g/cm³
• Vapor Pressure: 0.013mmHg at 25°C
• Refractive Index: 1.504
• Solubility: soluble in Methanol
• PKA: 3.23±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-4-METHYLBENZOTRIFLUORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-4-METHYLBENZOTRIFLUORIDE(25449-96-1)
• EPA Substance Registry System: 3-AMINO-4-METHYLBENZOTRIFLUORIDE(25449-96-1)

Safety Data

• Hazard Codes: T,Xn
• Statements: 36/37/38-52-22
• Safety Statements: 26-36/37/39
• RIDADR: 2810
• HazardClass: TOXIC
• Hazardous Substances Data: 25449-96-1(Hazardous Substances Data)

Usage

Uses

2-Methyl-5-trifluoromethylaniline

InChI:InChI=1/C9H8FN/c10-9-5-1-3-8(7-9)4-2-6-11/h1,3,5,7H,2,4H2

Upstream product

• 65754-26-9 2-methyl-5-trifluoromethylnitrobenzene 
• 56-23-5 tetrachloromethane 
• 95-53-4 o-toluidine 

Downstream Products

• 67191-98-4 2-Methyl-5-trifluormethylphenylisocyanat 
• 1445996-44-0 3-{4-[(2-methyl-5-trifluoromethylphenylaminooxalyl)amino]phenyl}hex-4-ynoic acid 
• 1429347-61-4 ethyl 3-(4-(N-isobutyl-N-(2-methyl-5-(trifluoromethyl)phenyl)sulfamoyl)phenyl)-2,2-dimethylpropanoate 
• 1429347-60-3 methyl 3-[4-({(2-methylpropyl)[2-methyl-5-(trifluoromethyl)phenyl]amino}sulfonyl)phenyl]propanoate 
• 1429347-15-8 3-(4-(N-isobutyl-N-(2-methyl-5-(trifluoromethyl)phenyl)sulfamoyl)phenyl)-2,2-dimethylpropanoic acid 
• 1429347-14-7 3-(4-(N-isobutyl-N-(2-methyl-5-(trifluoromethyl)phenyl)sulfamoyl)phenyl)propanoic acid 
• 1429347-30-7 2-methyl-N-(2-methylpropyl)-5-(trifluoromethyl)aniline 
• 1401688-55-8 C₂₂H₂₀F₃N₃O₃S 
• 288615-43-0 N-(2-methyl-5-trifluoromethyl-phenyl)-acetamide 
• 875155-19-4 2-amino-5-nitro-4-trifluoromethyl-benzoic acid methyl ester 
• 875155-18-3 2-acetylamino-5-nitro-4-trifluoromethyl-benzoic acid 
• 288615-44-1 2-Methyl-4-nitro-5-trifluoromethylacetanilide 

Relevant articles and documents

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The invention relates to an amino pyrimidine compound and a preparation method and application thereof. The amino pyrimidine compound has a structure as shown in a formula I. The formula is shown in the description. The compound is an inhibitor of an epidermal growth factor receptor (EGFR) kinase. The invention further relates to a medicine composition comprising the compound, a preparation methodand application thereof in preparation of anti-tumor medicines.

Pesticidal method using 2-phenylimidazole derivatives

The invention provides a method for the control of arthropod, plant nematode, helminth or protozoan pests using a 2-phenylimidazole derivative of the formula: STR1 wherein R1 represents hydrogen, alkyl (optionally substituted by alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, cyano, carboxy or alkoxycarbonyl), R2 and R3, each represents hydrogen, halogen, nitro, carboxy, cyano, alkoxycarbonyl, alkanoyl, or optionally alkyl substituted carbamoyl or sulphamoyl, or amino (optionally substituted by alkyl, alkoxycarbonyl or alkanoyl) or a group R, RO, RS, RSO or RSO2 in which R represents alkyl (optionally substituted by halogen), and Ar represents a group of the formula: STR2 wherein R4 and R6 each represents halogen or a group R, RO, RS, RSO or RSO2, and R5, R7 and R8 each represents a substituent as defined for R4 and R6, or represents hydrogen, hydroxy, carboxy, nitro, cyano, amino, alkylamino (optionally substituted by alkyl, alkoxycarbonyl or alkanoyl), alkoxycarbonyl or alkanoyl or a pesticidally acceptable salt thereof, with the exclusion of compounds in which R2 and R3 simultaneously represent hydrogen atoms, compositions for use in the method and novel compounds of formula I.