25457-99-2 Usage
Structure
2-((E)-(3-bromophenyl)methylideneamino)-2-methylpropan-1-ol
The compound has a structure that includes a 3-bromophenyl group, a methylidene amino group, a methyl group, and a hydroxyl group.
Functional groups
Bromine atom, Phenyl group, Amino group, Methyl group, Hydroxyl group
The compound contains various functional groups, such as a bromine atom, a phenyl group, an amino group, a methyl group, and a hydroxyl group, which contribute to its chemical properties and reactivity.
Double bond
Between the phenyl group and the methylidene amino group
Reagent and intermediate
Used in organic synthesis
2-[(E)-(3-bromophenyl)methylidene]amino-2-methylpropan-1-ol is utilized as a reagent and intermediate in various organic synthesis processes.
Application
Depends on specific use in research and industrial processes
The exact properties and applications of this chemical compound are determined by its particular use in research and industrial processes.
Check Digit Verification of cas no
The CAS Registry Mumber 25457-99-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,4,5 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 25457-99:
(7*2)+(6*5)+(5*4)+(4*5)+(3*7)+(2*9)+(1*9)=132
132 % 10 = 2
So 25457-99-2 is a valid CAS Registry Number.
25457-99-2Relevant articles and documents
Chemical Proteomics Approach for Profiling the NAD Interactome
?ileikyt?, Justina,Sundalam, Sunil,David, Larry L.,Cohen, Michael S.
supporting information, p. 6787 - 6791 (2021/05/29)
Nicotinamide adenine dinucleotide (NAD+) is a multifunctional molecule. Beyond redox metabolism, NAD+ has an equally important function as a substrate for post-translational modification enzymes, the largest family being the poly-ADP-ribose polymerases (PARPs, 17 family members in humans). The recent surprising discoveries of noncanonical NAD (NAD+/NADH)-binding proteins suggests that the NAD interactome is likely larger than previously thought; yet, broadly useful chemical tools for profiling and discovering NAD-binding proteins do not exist. Here, we describe the design, synthesis, and validation of clickable, photoaffinity labeling (PAL) probes, 2- and 6-ad-BAD, for interrogating the NAD interactome. We found that 2-ad-BAD efficiently labels PARPs in a UV-dependent manner. Chemical proteomics experiments with 2- and 6-ad-BAD identified known and unknown NAD+/NADH-binding proteins. Together, our study shows the utility of 2- and 6-ad-BAD as clickable PAL NAD probes.
N-substituted-2-amino-2-methyl-1-propanols as potential antitumor agents.
Billman,Koehler,May
, p. 767 - 769 (2007/10/10)
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