25458-11-1

Usage

Uses

Used in Organic Chemistry:
(6E)-4-bromo-6-[(2-hydroxy-1,1-dimethylethyl)amino]methylidenecyclohexa-2,4-dien-1-one is used as a reagent in chemical synthesis for its unique structure and potential to facilitate the creation of new compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (6E)-4-bromo-6-[(2-hydroxy-1,1-dimethylethyl)amino]methylidenecyclohexa-2,4-dien-1-one is used as a compound for research and development. Its potential biological activities make it a candidate for the development of new drugs, although further research is needed to fully understand its properties and potential uses.

Upstream product

• 124-68-5 2-Amino-2-methyl-1-propanol 
• 1761-61-1 5-bromosalicyclaldehyde 

Relevant academic research and scientific papers

Ligand-Flexibility Controlled and Solvent-Induced Nuclearity Conversion in CuII-Based Catecholase Models: A Deep Insight Through Combined Experimental and Theoretical Investigations

A Schiff-base ligand, 4-bromo-2-[(2-hydroxy-1,1-dimethylethylimino)methyl]phenol (HL1), and its reduced analogue 4-bromo-2-[(2-hydroxy-1,1-dimethylethylamino)methyl]phenol (HL2) have been synthesized. Treatment of HL1and H

Unveiling the effects of the: In situ generated arene anion radical and imine radical on catecholase like activity: A DFT supported experimental investigation

Two new dinuclear nickel(ii) complexes namely [Ni2(L1)2(OAc)2(H2O)2]·CH3CN (1) and [Ni2(L2)2(SCN)2(CH3OH)2]·CHs

Racemization of secondary alcohols catalyzed by ruthenium: Application to chemoenzymatic dynamic resolution

In this paper, we have shown that the [RuCl2(p-cymene)] 2 complex associated with simple hemisalen ligands is able to racemize (S)-1-phenylethanol. The influence on the racemization process of the ligand's structure as well as the nature of a co-catalyst have been evaluated and optimized. This [RuCl2(p-cymene)]2/Ligand/TEMPO racemization system was then associated with the Candida Antarctica B lipase in order to carry out dynamic kinetic resolution experiments on rac-phenylethanol. This led us to identify the best conditions for effective DKR, which was then applied to various secondary benzylic and aliphatic alcohols. It was thus possible to obtain (R)-1-cyclohexylethyl acetate from rac-1-cyclohexylethanol in quantitative conversion and with high enantioselectivity (98%).

RING-CHAIN TAUTOMERISM IN 1,3-THIAZOLIDINES

NMR spectroscopy was applied to study ring-chain tautomeric equilibria in several substituted 1,3-thiazolidines.The system highly prefers the ring form and only in the case of 2-(2'-hydroxy-5'-bromophenyl)-1,3-benzothiazoline (2d) 1H and 13C NMR spectra r