25458-47-3Relevant academic research and scientific papers
Preparation method of sulfasalazine impurity D
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Paragraph 0040; 0045; 0051; 0056, (2020/07/24)
The invention discloses a preparation method of a sulfasalazine impurity D, belongs to the field of drug impurity synthesis, and provides the preparation method of the sulfasalazine impurity D, whichis reasonable in process design, strong in operability,
Reversible heterochiral aggregation/dissociation of bis(2-hydroxyphenyl) diamides driven by UV/Vis irradiation
Nojiri, Akihiro,Kumagai, Naoya,Shibasaki, Masakatsu
supporting information; experimental part, p. 2137 - 2141 (2012/04/10)
Light to dissolve: (R)- and (S)-diamides bearing a hydrogen-bonding framework (red in picture) and a trans-azobenzene unit (blue) form an insoluble heterochiral aggregate, which can be dissolved by photoisomerization of the azobenzene unit to the cis conformation by UV irradiation (365-nm). The insoluble aggregate was formed again by subsequent irradiation with visible light (>422-nm). The precipitation and dissolution is manifestly reversible. Copyright
