254729-47-0Relevant academic research and scientific papers
A Highly Active and Selective Catalyst System for the Baylis-Hillman Reaction
You, Jingsong,Xu, Juhua,Verkade, John G.
, p. 5054 - 5056 (2003)
A key role for sulfur and the potential for Nax→P intrabridgehead interactions are invoked to explain the impressive effect of the cocatalyst (shown in color) in the TiCl4-mediated Baylis-Hillman reaction [Eq. (1)]. Even sterically h
Cyclic enones as substrates in the Morita-Baylis-Hillman reaction: Surfactant interactions, scope and scalability with an emphasis on formaldehyde
Schwartz, Brett D.,Porzelle, Achim,Jack, Kevin S.,Faber, Jonathan M.,Gentle, Ian R.,Williams, Craig M.
experimental part, p. 1148 - 1154 (2010/01/15)
Traditionally, cyclic enones and formalin are reactants notorious for displaying problematic behaviour (i.e., poor solubility and low yields) under Morita-Baylis-Hillman (MBH) reaction conditions. The body of research presented herein focuses on the use o
Evaluating the Baylis-Hillman reaction of cyclic enones using surfactants in water
Porzelle, Achim,Williams, Craig M.,Schwartz, Brett D.,Gentle, Ian R.
, p. 2923 - 2926 (2007/10/03)
Conjugated cyclic enones react smoothly in water with a variety of aldehydes (Baylis-Hillman reaction) in the presence of surfactants above their critical micelle concentrations (CMC). Georg Thieme Verlag Stuttgart.
Superior amine catalysts for the Baylis-Hillman reaction: The use of DBU and its implications
Aggarwal, Varinder K.,Mereu, Andrea
, p. 2311 - 2312 (2007/10/03)
DBU, which is normally regarded as a hindered and non-nucleophilic base, is in fact the optimum catalyst for the Baylis-Hillman reaction, providing adducts at much faster rates than using DABCO or 3HQD; the scope of the Baylis-Hillman reaction is enhanced
