254734-73-1Relevant articles and documents
An active catalyst for Diels-Alder reaction of indol with o-benzoquinone
Sedaghat,Zein
, p. 908 - 910 (2017)
The Diels-Alder reaction of indol with masked o-benzoquinone was studied. The stereo selectivity of this reaction by heterogeneous catalysis is improved. This catalyst was prepared by surface modification of nanoporous silica gel with cerium ion in aqueou
Studies on photochemical rearrangement of non-oxygenated bicyclo[2.2.2]octenones and mono-oxygenated bicyclo[2.2.2]octenones from masked o-benzoquinones: Access to protoilludane and marasmane skeletons
Hung, Wei-Chun,Chen, Yung-Ching,Niu, Guang-Hao,Chuang, Gary J.
, p. 383 - 398 (2020/02/04)
In this work, we described flexible approaches to protoilludane-like (5,6,4-tricyclic ring) and marasmane-like (5,6,3-tricyclic ring) skeletons with naturally occurring cis/anti/cis stereochemistry using photochemical rearrangement of bicyclo[2.2.2]octeno
A Mild meta-Selective C–H Alkylation of Catechol Mono-Ethers
Vitaku, Edon,Njardarson, Jon T.
supporting information, p. 3679 - 3683 (2016/08/16)
Catechol mono-ethers are an important class of phenols. They are found in a number of pharmaceuticals, flavoring agents, perfumes, and are used for the preparation of numerous drugs. Herein, we report a mild meta-selective C–H alkylation of these phenols, which is enabled by a cascade of oxidative dearomatization – radical addition – rearomatization process. The method is compatible with reactive functional groups on the parent arenol, such as olefins and halides. Primary, secondary, and teriary alkyl groups can be used, the source of which is most commonly an alkylborane. This process is operationally simple, does not require heating and generally proceeds in good yields.
