254749-11-6 Usage
Uses
Used in Pharmaceutical Industry:
2-Chloro-4-cyanobenzenesulfonyl Chloride is used as a key intermediate in the synthesis of Hydroxysulfonyloxaazaspirodecanylaminopropoxybenzenesulfonamide derivatives. These derivatives serve as beta-3 adrenergic receptor modulators, which have potential applications in the treatment of various medical conditions, such as obesity and related metabolic disorders, by modulating the activity of the beta-3 adrenergic receptor.
Check Digit Verification of cas no
The CAS Registry Mumber 254749-11-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,4,7,4 and 9 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 254749-11:
(8*2)+(7*5)+(6*4)+(5*7)+(4*4)+(3*9)+(2*1)+(1*1)=156
156 % 10 = 6
So 254749-11-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H3Cl2NO2S/c8-6-3-5(4-10)1-2-7(6)13(9,11)12/h1-3H
254749-11-6Relevant articles and documents
NOVEL TETRAZOLE COMPOUNDS AND THEIR USE IN THE TREATMENT OF TUBERCULOSIS
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Page/Page column 77, (2019/03/05)
The invention relates to a compound of Formula (I) or a pharmaceutically acceptable salt thereof and their use in therapy, for example in the treatment of mycobacterial infections or in the treatment of diseases caused by mycobacterium, such as tuberculosis.
N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS
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Page/Page column 93; 94, (2014/12/12)
A compound of formula (I), or a pharmaceutically acceptable salt thereof and a pharmaceutical composition comprising the compound. The compound is an inhibitor of interactions between S100A9 and interaction partners such as RAGE, TLR4 and EMMPRIN and as such is useful in the treatment of disorders such as cancer, autoimmune disorders, inflammatory disorders and neurodegenerative disorders.
