25488-37-3 Usage
Uses
Used in Pharmaceutical Industry:
1,12-Epoxy-9H-indolo[3,2,1-de]phenanthridine,9a,10,11,12,13,13a-hexahydro-2,9,9,12-tetramethyl-, (9aR,12S,13aS)-rel-(+)is used as a potential therapeutic agent for the treatment of various types of cancer. Its complex molecular structure and specific stereochemistry allow it to interact with cellular targets, such as proteins and enzymes, that are involved in cancer cell growth and survival. By modulating these targets, the compound may exhibit anti-cancer properties and contribute to the development of novel cancer treatments.
Used in Chemical Research:
1,12-Epoxy-9H-indolo[3,2,1-de]phenanthridine,9a,10,11,12,13,13a-hexahydro-2,9,9,12-tetramethyl-, (9aR,12S,13aS)-rel-(+)can be used as a starting material or a key intermediate in the synthesis of other complex organic compounds. Its unique structural features make it an interesting candidate for further chemical modifications and exploration of its potential applications in various fields, such as materials science, pharmaceuticals, and agrochemicals.
Used in Drug Delivery Systems:
Similar to gallotannin, 1,12-Epoxy-9H-indolo[3,2,1-de]phenanthridine,9a,10,11,12,13,13a-hexahydro-2,9,9,12-tetramethyl-, (9aR,12S,13aS)-rel-(+)may also benefit from the development of novel drug delivery systems to enhance its applications and efficacy against cancer cells. By employing various organic and metallic nanoparticles as carriers, the compound's delivery, bioavailability, and therapeutic outcomes can be improved, potentially leading to more effective cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 25488-37-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,4,8 and 8 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 25488-37:
(7*2)+(6*5)+(5*4)+(4*8)+(3*8)+(2*3)+(1*7)=133
133 % 10 = 3
So 25488-37-3 is a valid CAS Registry Number.
25488-37-3Relevant academic research and scientific papers
Efficient construction of pyrano [3, 2-a]carbazoles: Application to a biomimetic total synthesis of cyclized monoterpenoid pyrano [3, 2-a]carbazole Alkaloids
Hesse, Ronny,Gruner, Konstanze K.,Kataeva, Olga,Schmidt, Arndt W.,Kn?lker, Hans-Joachim
, p. 14098 - 14111 (2013/11/06)
We have developed a highly efficient route to 2-hydroxy-3-methyl-carbazole (1) via a palladium-catalyzed construction of the carbazole skeleton. Using 1 as relay compound, different methods for annulations of pyran rings by reaction with terpenoid building blocks have been tested. The Lewis acid promoted reaction of 1 with prenal (21) opened up an efficient route to girinimbine (3) and the corresponding reaction with citral (25) afforded mahanimbine (5). Oxidation of compounds 3 and 5 provided murraya-cine (4) and murrayacinine (6). Following the biogenetic proposal, mahanim-bine (5) has been exploited for efficient biomimetic syntheses of the cyclized monoterpenoid pyrano[3, 2-a]carbazole alkaloids cyclomahanimbine (7), maha-nimbidine (8) and bicyclomahanimbine (9). The interconversions of 5, 7, 8 and 9 are described and mechanistic implications are discussed. Structural assignments are unambiguously verified by X-ray crystal structure determinations. Moreover, cyclomahanimbine (7) was transformed into murrayazolinine (10) and exozoline (11).
