254885-82-0Relevant academic research and scientific papers
Synthesis and hypoglycaemic activity of some new flavone derivatives. Part 1: Flavonylsulphonylurea derivatives
Bozdag, Oya,Verspohl, Eugen J.,Ertan, Rahmiye
, p. 435 - 438 (1999)
A new series of flavonyl-3'-sulphonylurea derivatives (1-7) was prepared by reaction of several isocyanates with flavone-3'-sulphonamide (III). The prepared compounds were tested for their insulinotropic activities in INS-1 cells. Compounds 1 and 4 were able to increase insulin release in the presence of 8.3 mM glucose at least at the higher concentrations used.
Flavone-3′-sulfonamide
Kendi, Engin,Oezbey, Sueheyla,Bozdag, Oya,Ertan, Rahmiye
, p. 457 - 458 (2007/10/03)
In the title molecule, C15H11NO4S, the phenyl and benzene rings are quite planar, with maximum deviations from planarity of 0.009 (2) and 0.004 (1) A, respectively. The γ-pyrone ring deviates from planarity and makes a dihedral angle of 8.3 (3)° with the 2-phenyl substituent. The sulfonamide group is involved in N-H...O hydrogen bonding.
