254892-82-5 Usage
Type of compound
Cyclobutanecarboxylic acid derivative
Contains
a. Amino group
b. Boron atom
Potential applications
a. Boronic acid-based drug design
b. Organic synthesis
Unique structure
The presence of the boron atom makes it an interesting candidate for medicinal chemistry and pharmaceutical development.
Importance in fields
a. Medicinal chemistry
b. Development of new pharmaceuticals
Boronic acids
a. Versatile building blocks
b. Construction of new organic molecules
c. Demonstrated important applications in different fields
Check Digit Verification of cas no
The CAS Registry Mumber 254892-82-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,4,8,9 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 254892-82:
(8*2)+(7*5)+(6*4)+(5*8)+(4*9)+(3*2)+(2*8)+(1*2)=175
175 % 10 = 5
So 254892-82-5 is a valid CAS Registry Number.
254892-82-5Relevant articles and documents
4-Dihydroxyborylphenyl Analogues of 1-Aminocyclobutanecarboxylic Acids: Potential Boron Neutron Capture Therapy Agents
Srivastava, Rajiv R.,Singhaus, Robert R.,Kabalka, George W.
, p. 8495 - 8500 (2007/10/03)
A series of 4-dihydroxyborylphenyl analogues of an unnatural α-amino acid, 1-aminocyclobutanecarboxylic acid (ACBC), was synthesized. Varying numbers of methylene units were introduced between the 4-boronophenyl and ACBC moieties in order to introduce different degrees of lipophilicity into the molecules. The key step in the syntheses was the preparation of the precursor p-boronophenyl-substituted cyclobutanones which were subsequently converted to the desired amino acids via the Bucherer-Strecker reaction.
