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3-(4-Boronophenyl)cyclobutanone is a chemical compound characterized by the presence of a boron atom, a phenyl group, and a cyclobutanone ring. It is a yellow crystalline solid that serves as a valuable building block in organic synthesis. Known for its reactivity in various chemical reactions such as cycloadditions and cross-coupling reactions, 3-(4-BORONOPHENYL)CYCLOBUTANONE has garnered interest for its potential applications in pharmaceuticals, materials science, and the advancement of synthetic methodologies. Furthermore, it has been utilized in the synthesis of biologically active molecules, establishing its role as a versatile intermediate in organic chemistry.

254893-03-3

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254893-03-3 Usage

Uses

Used in Organic Synthesis:
3-(4-Boronophenyl)cyclobutanone is used as a building block for the synthesis of complex organic molecules, leveraging its ability to participate in cycloadditions and cross-coupling reactions. Its unique structure allows for the creation of a wide range of chemical entities, making it a valuable component in the development of new compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-(4-Boronophenyl)cyclobutanone is used as a key intermediate in the synthesis of biologically active molecules. Its reactivity and structural features enable the production of potential drug candidates, contributing to the discovery and development of new therapeutic agents.
Used in Materials Science:
3-(4-Boronophenyl)cyclobutanone is utilized in materials science for the development of novel materials with specific properties. Its integration into the molecular structure of these materials can influence characteristics such as stability, reactivity, and other functional attributes, thereby expanding the scope of materials available for various applications.
Used in Development of Synthetic Methodologies:
3-(4-Boronophenyl)cyclobutanone plays a role in the advancement of synthetic methodologies, providing a platform for chemists to explore new reaction pathways and mechanisms. Its versatility in undergoing various chemical transformations facilitates the creation of innovative synthetic routes, enhancing the efficiency and selectivity of chemical processes.

Check Digit Verification of cas no

The CAS Registry Mumber 254893-03-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,4,8,9 and 3 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 254893-03:
(8*2)+(7*5)+(6*4)+(5*8)+(4*9)+(3*3)+(2*0)+(1*3)=163
163 % 10 = 3
So 254893-03-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H11BO3/c12-10-5-8(6-10)7-1-3-9(4-2-7)11(13)14/h1-4,8,13-14H,5-6H2

254893-03-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name [4-(3-oxocyclobutyl)phenyl]boronic acid

1.2 Other means of identification

Product number -
Other names 3-(4-boronophenyl)cyclobutanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:254893-03-3 SDS

254893-03-3Relevant academic research and scientific papers

4-Dihydroxyborylphenyl Analogues of 1-Aminocyclobutanecarboxylic Acids: Potential Boron Neutron Capture Therapy Agents

Srivastava, Rajiv R.,Singhaus, Robert R.,Kabalka, George W.

, p. 8495 - 8500 (2007/10/03)

A series of 4-dihydroxyborylphenyl analogues of an unnatural α-amino acid, 1-aminocyclobutanecarboxylic acid (ACBC), was synthesized. Varying numbers of methylene units were introduced between the 4-boronophenyl and ACBC moieties in order to introduce different degrees of lipophilicity into the molecules. The key step in the syntheses was the preparation of the precursor p-boronophenyl-substituted cyclobutanones which were subsequently converted to the desired amino acids via the Bucherer-Strecker reaction.

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