2549-47-5Relevant academic research and scientific papers
Aryldifluoromethylphosphonic acids with sulfur-containing substituents as PTP-1B inhibitors
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, (2008/06/13)
The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases,
Structure-based design and synthesis of small molecule protein-tyrosine phosphatase 1B inhibitors
Yao, Zhu-Jun,Ye, Bin,Wu, Xiong-Wu,Wang, Shaomeng,Wu, Li,Zhang, Zhong-Yin,Burke Jr., Terrence R.
, p. 1799 - 1810 (2007/10/03)
Protein-tyrosine phosphatase (PTP) inhibitors are attractive as potential signal transduction-directed therapeutics which may be useful in the treatment of a variety of diseases. We have previously reported the X-ray structure of 1,1-difluoro-1-(2-naphtha
Catalyst for carbonylating naphthalene mono- and disulfonates and process using said catalyst
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, (2008/06/13)
A cobalt based catalyst, and the method for preparing it, are disclosed. The catalyst is obtained from the reaction between NaCo(CO)4 and s-trichloro triazine and is advantageously used in the processes of carbonylation of naphthalene mono- and disulfonates in order to yield naphthalene esters and acids.
Catalyst for carbonylating naphthalene mono- and disulfonates and process using said catalyst
-
, (2008/06/13)
A cobalt based catalyst, and the method for preparing it, are disclosed. The catalyst is obtained from the reaction between NaCo(CO)4 and s-trichloro triazine and is advantageously used in the processes of carbonylation of naphthalene mono- and disulfonates in order to yield naphthalene esters and acids.
Cobalt-catalyzed methoxycarbonylation of naphthalene mono- and di-sulfonates to naphthalene mono- and di-esters
Cometti, Giuseppe,vosel, Annick Du,Francalanci, Franco,Santi, Roberto,Cabri, Walter,Foa, Marco
, p. C13 - C14 (2007/10/02)
The methoxycarbonylation of naphthalene mono- and di-sulfonates under mild reaction conditions catalyzed by cobalt complexes generated in situ from either -/Me2SO4 or -/BrCH2COOEt is reported.
