254907-06-7Relevant academic research and scientific papers
Enantioselective synthesis of the key intermediate of the acyl-CoA: Cholesterol acyltransferase (ACAT) inhibitor (R-106578) using 2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (BINAP)-Ru(OAc)2 as a catalyst
Murakami,Kobayashi,Hirai
, p. 1567 - 1569 (2007/10/03)
Acidic segment of an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor, R-106578 was synthesized by enantioselective hydrogenation of the Z-olefine (9-(Z)) using (R)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl (BINAP)-Ru(OAc)2 as a catalys
