254973-98-3

Upstream product

• 73918-56-6 4-Bromophenethylamine 
• 29568-33-0 2-methoxy-5-chlorobenzoyl chloride 
• 64269-79-0 Carbonyldiimidazole 
• 3438-16-2 5-chloro-2-methoxybenzoic acid 

Downstream Products

• 254974-02-2 5-[2-(5-chloro-2-methoxybenzamido)ethyl]-2-phenyl-benzenesulfonamide 
• 254973-99-4 2-bromo-5-[2-(5-chloro-2-methoxybenzamido)ethyl]benzenesulfonamide 

Relevant academic research and scientific papers

2,5-substituted benzolsulfonylureas and thioureas methods for the production thereof use thereof and pharmaceutical preparations containing the same

Novel 2,5-substituted benzolsulfonyl ureas and thioureas of formula (I) as illustrated in the disclosure. The compounds are useful active ingredients for medicaments. The compounds of formula (I) act as inhibitors on ATP-sensitive potassium canals and are

Cardioselective KATP channel blockers derived from a new series of m-anisamidoethylbenzenesulfonylthioureas

Sulfonylthioureas exhibiting cardioselective blockade of ATP-sensitive potassium channels (KATP channels) were discovered by stepwise structural variations of the antidiabetic sulfonylurea glibenclamide. As screening assays, reversal of rilmaka