25499-90-5

Basic information

• Product Name: 3-Epioleanolic acid
• Synonyms: 3-Epioleanolic acid;(3α)- 3-Hydroxy- olean-12-en-28-oic acid;(3alpha)-3-Hydroxy-olean-12-en-28-oic acid;3-Epioleanic acid;3-epi-Oleanic acid;Epioleanolic acid
• CAS NO: 25499-90-5
• Molecular Formula: C₃₀H₄₈O₃
• Molecular Weight: 456.7
• Product Categories: Pentacyclic Triterpenes
• Mol File: 25499-90-5.mol
• Article Data: 16

Chemical Properties

• Melting Point: 297-299 °C(Solv: methanol (67-56-1))
• Boiling Point: 553.5±50.0 °C(Predicted)
• Appearance: /
• Density: 1.10±0.1 g/cm3(Predicted)
• PKA: 4?+-.0.70(Predicted)
• CAS DataBase Reference: 3-Epioleanolic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Epioleanolic acid(25499-90-5)
• EPA Substance Registry System: 3-Epioleanolic acid(25499-90-5)

Safety Data

• Hazardous Substances Data: 25499-90-5(Hazardous Substances Data)

Usage

Uses

3-epi-Oleanolic Acid is a possible drug candidate for treating Alzheimer’s disease. It is an important reagent in preparation of 3-O-β-chacotriosyl oleanane-type triterpenoids which are potential H5N1 entry inhibitors.

Upstream product

• 90452-93-0 silphioside E 
• 76742-94-4 oleanolic acid 3-O-β-D-glucopyranosyl-(1-4)-β-D-glucopyranosyl-(1-4)-β-D-xylopyranosyl-(1-3)-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 102191-02-6 entada saponin II 
• 75799-17-6 oleanolic acid 3-O-β-D-xylopyranosyl-(1-3)-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 75799-17-6 oleanolic acid 3-O-β-D-ribopyranosyl-(1-3)-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 75799-17-6 hishoushi-saponin A 
• 75799-17-6 saponin V 
• 58546-61-5 silphioside A 
• 72629-77-7 oleanolic acid 3-O-β-D-glucopyranosyl-(1-4)-β-D-xylopyranosyl-(1-3)-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 99633-18-8 rotundinoside B 
• 99633-19-9 rotundinoside C 
• 80145-52-4 saponin-D 
• 80135-33-7 saponin-C 
• 29014-88-8 saponin-D methylester 

Downstream Products

• 1721-57-9 Oleanolsaeuremethylester-acetat 
• 17990-42-0 Oleanonsaeure 
• 1724-17-0 3β-hydroxy-olean-12-en-28-oic acid methyl ester 
• 1724-17-0 oleanolic acid, methyl ester 
• 1272616-97-3 oleanolic acid benzyl ester 
• 1401414-24-1 C₃₇H₅₀BrNO₄ 

Relevant articles and documents

A new triterpenoid glycoside from the seeds of Glinus lotoides

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TRITERPENE GLYCOSIDES OF Silphium perfoliatum. V. THE STRUCTURE OF SILPHIOSIDE A

From the epigeal part of Silphium perfoliatum L. we have isolated glycoside F, identified as oleanolic acid 3-O-β-D-glucopyranosiduronic acid and a new triterpene glycoside - silphioside A - for which the structure of oleanolic acid 28-O-β-D-glucopyranoside 3-O-(methyl β-D-glucopyranosiduronate) has been established.

Saponins from the leaves of Aralia elata SEEM. (Araliaceae)

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SAPONINS FROM ROOTS OF MOMORDICA COCHINCHINENSIS

Ten minor saponins, momordins Ia-Ie and IIa-IIe, were isolated from the root of Momordica cochinchinensis, along with the known major saponins, momordins I and II.Their structures were established on the basis of chemical and spectroscopic analysis.The structures of the two new saponins were assigned as 3β-(((O-β-D-xylopyranosyl-(1-->2)-O-β-D-xylopyranosyl-(1-->3))O-β-D-glucopyranuronosyl)oxy)-olean-12-ene-28-oic acid for momordin Id and momordin Id-28-β-D-glucopyranosyl ester for momordin IId.It was confirmed that the genuine saponin present in the root was not the monodesmoside but the bisdesmoside, though the former is the major component in the dry root. Key word Index--Momordica cochinchinensis; Cucurbitaceae; saponin; momordin; oleanolic acid; monodesmoside; bisdesmoside; 13C NMR.