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1724-17-0 Usage

General Description

Methyl oleanolate is a chemical compound derived from oleanolic acid, a naturally occurring pentacyclic triterpenoid found in various plant species. It is commonly used in the pharmaceutical and cosmetic industries for its anti-inflammatory, anti-oxidant, and anti-tumor properties. Methyl oleanolate has been studied for its potential as a drug candidate for the treatment of various diseases, including cancer, diabetes, and cardiovascular disorders. Its ability to inhibit the growth of cancer cells and reduce inflammation makes it a promising compound for future therapeutic applications. Additionally, it has also shown potential in skin care products for its anti-aging and skin rejuvenating properties. Overall, methyl oleanolate is a versatile compound with a range of potential medicinal and cosmetic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1724-17-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,2 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1724-17:
70 % 10 = 0
So 1724-17-0 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017


1.1 GHS Product identifier

Product name methyl (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate

1.2 Other means of identification

Product number -
Other names methyl oleanoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1724-17-0 SDS

1724-17-0Relevant articles and documents

Water-induced gel formation of an oleanlic acid-adenine conjugate and the effects of uracil derivative on the gel stability

Lu, Jinrong,Hu, Jun,Liu, Chulong,Gao, Hongxin,Ju, Yong

, p. 9576 - 9580,5 (2012)

The conjugate of oleanlic acid with adenine was synthesized and it could be gelled in mixed solvents of THF and water, but no gel was formed in the single organic solvent. The self-aggregation behaviour and physical properties of the organogel were characterized by 1H NMR, FT-IR, and scanning electron microscopy. The morphology and the stability of the gel were remarkably affected by the uracil derivative through destroying hydrogen-bonding.

Studies on differentiation-inducing activities of triterpenes


, p. 401 - 405 (1992)

Differentiation-inducing activity of over 180 extracts of crude drugs and plants was tested using mouse myeloid leukemia cell line (M1). The methanol extracts of clove (Syzygium aromaticum MERRILL et PERRY, Myrtaceae) showed remarkable induction of differentiation of M1 cells into macrophage-like cells. From the extract, oleanolic acid (1) and crategolic acid (2) were isolated as the active components. We also tested other triterpenes, such as oleananes, ursanes and dammaranes, to investigate the structure-activity relationship. Some triterpene aglycones showed differentiation inducing activity, but triterpene glycosides showed little activity. Furthermore, the differentiation-inducing activity of these triterpene compounds was tested against human acute promyelocytic leukemia cell line (HL-60).


Schteingart, Claudio D.,Pomilio, Alicia B.

, p. 2907 - 2910 (1984)

Oleanolic acid 3-O-(3'-O-α-L-rhamnopyranosyl)-β-D-glucuronopyranoside and its 28-O-β-D-glucopyranosyl ester have been isolated from aerial parts of Zexmenia buphthalmiflora.The chemotaxonomical significance of the transfer of Wedelia buphthalmiflora to Zexmenia buphthalmiflora is discussed. Key Word Index - Zexmenia buphthalmiflora; Wedelia buphthalmiflora; Heliantheae; Compositae; structure elucidation; saponins; oleanolic acid 3-O-(3'-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside; oleanolic acid 3-O-(3'-O-α-L-rhamnopyranosyl)-β-D-glucuronopyranoside-28-O-β-D-glucopyranoside.

Partial synthesis of krukovines A and B, triterpene ketones isolated from the Brazilian medicinal plant Maytenus krukovii


, p. 1174 - 1177 (1997)

Krukovines A (1) and B (2), triterpene ketones isolated from the Brazilian medicinal plant 'chuchuhuasi' (Maytenus krukovii), were synthesized in eight steps from the commercially available oleanolic acid and ursolic acid, respectively.

Synthesis and anion recognition of a novel oleanolic acid-based cyclic dimer

Hu, Jun,Li, Ruofan,Lu, Jinrong,Ju, Yong

, p. 4211 - 4214 (2011)

A novel cyclic dimer based on oleanolic acid was synthesized using click chemistry and it showed remarkable selectivity and affinity to bind fluoride ion through C-H...F hydrogen bond interactions which involved the delocalization of proton in methylene.

Radical-Induced Deoxygenation of Primary Alcohols

Barton, Derek H. R.,Motherwell, William B.,Stange, Andreas

, p. 743 - 745 (1981)


Patkhullaeva et al.

, (1972)

On the saponins from the leaves of Fatsia japonica Decne. et Planch.


, p. 92 - 94 (1979)


Type and position of linkage govern the cytotoxicity of oleanolic acid rhodamine B hybrids

Heise, Niels,Hoenke, Sophie,Simon, Vivienne,Deigner, Hans-Peter,Al-Harrasi, Ahmed,Csuk, René

, (2021/06/21)

Oleanolic acid/rhodamine B hybrids exhibit different cytotoxicity depending on the way these two structural elements are linked. While a hybrid holding a piperazinyl spacer at C-28 proved to be cytotoxic in the nano-molar concentration range, hybrids with a direct linkage of the Rho B residue to C-3 of the triterpenoid skeleton are cytotoxic only in the low micro-molar concentration range without any selectivity. This once again underlines the importance of selecting the right spacer and the most appropriate position on the skeleton of the triterpene to achieve the most cytotoxic hybrids possible.

Application of methyl isocycloenone oleanolate to preparation of medicine for preventing and treating viral hepatitis B


Paragraph 0029; 0032-0033, (2020/11/23)

The invention relates to an application of methyl isocycloenone oleanolate to preparation of a medicine for preventing and treating viral hepatitis B, and particularly provides an application of 3 beta-hydroxyl-12-carbonyl oleanane-13 (18)-alkene-28-carboxylic acid methyl ester to preparation of a medicine for resisting hepatitis B virus infection diseases. A compound has remarkable effect of inhibiting the activity of HBsAg and HBeAg secreted by HepG2.2. 15 cells, the intensity of inhibiting HBsAg and HBeAg secretion at the concentration of 100 micrograms/milliliter on the eighth day exceedsthat of positive control medicines namely alpha-interferon and lamivudine, and the inhibition rate of the compound on HBV-DNA replication is higher than 97% under the concentration. The result shows that the methyl isocycloenone oleanolate can be expected to be used for preparing non-nucleoside medicines for treating hepatitis B virus infection diseases; and specifically, the compound has the functions of being used for preparing an HBV-DNA inhibitor, an HBsAg inhibitor and an HBeAg inhibitor, and the preparation method is simple in step, low in cost, wide in raw material source and easy for industrial production.

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