2550-61-0

Usage

Uses

Used in Cell Electrophysiology:
Cesium methanesulfonate is used as a current carrier for [application reason] its ability to block potassium (K+) channels and not be transported through chloride (Cl-) channels. This property makes it a valuable component in intracellular recording solutions of electrodes for patch clamp techniques, which are essential for studying the electrical properties of cells and their ion channels.
Used in Patch Clamp Recording System:
In the application industry of cell electrophysiology, cesium methanesulfonate is used as a supplement in intracellular solution for the patch clamp recording system. Its role in this system is to facilitate the study of ion channel activity and cell membrane potential, which are crucial for understanding various cellular processes and developing targeted therapies for a range of diseases.

InChI:InChI=1/CH4O3S.Cs/c1-5(2,3)4;/h1H3,(H,2,3,4);/q;+1/p-1/rCH3CsO3S/c1-6(3,4)5-2/h1H3

Upstream product

• 924-80-1 2-octyl mesylate 
• 3396-11-0 cesium acetate 
• 17265-04-2 cesium benzoate 
• 75-75-2 methanesulfonic acid 

Relevant academic research and scientific papers

PREPARATION, PROPERTIES, AND CHARACTERIZATION OF METHANESULFONATO COMPLEXES OF ARSENIC(III), ANTIMONY(III), AND BISMUTH(III)

Arsenic(III), antimony(III), and bismuth(III) oxides, sodium arsenite and bismuthate react with methanesulfonic anhydride, (CH3)2S2O5, to yield M(SO3CH3)3 (M = As(III), Sb(III), and Bi(III), Na, and Na, respectively, in quantitative yield.Reaction of arsenic(III) oxide with pure methanesulfonic acid yields oxo(methanesulfonato)arsenic(III), AsO(SO3CH3), which behaves as a non-electrolyte in 100percent methanesulfonic acid.The compounds have been characterized by elemental analysis, conductance, infrared. 1H nmr and thermal measurements.Their properties have been studied by ligand substitution and complex formation reactions.The M(SO3CH3)3 (M = As(III), Sb(III), and Bi(III)) compounds are capable of functioning both as Lewis acids and bases.These compounds exhibit basic behaviour in 100percent methanesulfonic acid.The synthesis of complex methanesulfonates Cs (M = As(III), Sb(III), and Bi(III) is also described.

An Assessment of the Causes of the "Cesium Effect"

Cesium alkanoates (chiefly the propionate) have been investigated for their solubility, nucleophilic, reactivity and degree of ion pairing in dimethylformamide (DMF) and, in some cases, dimethyl sulfoxide (DMSO) solutions. 133Cs NMR has been used to establish the degree of ion pairing.From the data obtained it is concluded that the cesium ion is virtually completely solvated and that the carboxylates are essentially free and highly reactive.The consequences of this effect on macrocyclization by means of nucleophilic substitution are discussed.