255045-00-2Relevant academic research and scientific papers
The synthesis of bicyclic lactam based His-Pro building blocks: The effect of substituent polarity on an intramolecular bond migration
Chu, Wenhua,Moeller, Kevin D.
, p. 7939 - 7943 (2007/10/03)
A strategy for constructing bicyclic lactam amino acid building blocks with imidazole sidechains is reported. The synthetic route described utilizes an electrochemical amide oxidation to functionalize a proline derivative, and then a sequential cyclizatio
