255065-87-3

Upstream product

• 591-31-1 3-methoxy-benzaldehyde 
• 134-81-6 benzil 
• 484-47-9 lophine 
• 100-52-7 benzaldehyde 
• 105-39-5 chloroacetic acid ethyl ester 

Downstream Products

• 1296625-59-6 N₁-(2,4,5-triphenylimidazol-1-ylethanoyl)-N₄-(4-chlorophenyl)thiosemicarbazide 
• 1296625-53-0 N₁-(2,4,5-triphenylimidazol-1-ylethanoyl)-N₄-(4-methoxyphenyl)thiosemicarbazide 
• 1296625-57-4 N₁-(2,4,5-triphenylimidazol-1-ylethanoyl)-N₄-(4-fluorophenyl)thiosemicarbazide 
• 1296625-55-2 N₁-(2,4,5-triphenylimidazol-1-ylethanoyl)-N₄-(4-methylphenyl)thiosemicarbazide 
• 1296625-65-4 4-(4-fluorophenyl)-5-(2,4,5-triphenylimidazol-1-ylmethyl)-4H-1,2,4-triazol-3-thiol 
• 1296625-67-6 4-(4-chlorophenyl)-5-(2,4,5-triphenylimidazol-1-ylmethyl)-4H-1,2,4-triazol-3-thiol 
• 1296625-69-8 (4-methoxyphenyl)-[5-(2,4,5-triphenylimidazol-1-ylmethyl)-1,3,4-thiadiazol-2-yl]-amine 
• 1296625-71-2 (4-methylphenyl)-[5-(2,4,5-triphenylimidazol-1-ylmethyl)-1,3,4-thiadiazol-2-yl]-amine 
• 1296625-73-4 (4-fluorophenyl)-[5-(2,4,5-triphenylimidazol-1-ylmethyl)-1,3,4-thiadiazol-2-yl]-amine 
• 1296625-75-6 (4-chlorophenyl)-[5-(2,4,5-triphenylimidazol-1-ylmethyl)-1,3,4-thiadiazol-2-yl]-amine 
• 1296625-77-8 N-[2-(4-methoxyphenylimino)-4-oxothiazolidin-3-yl]-2-(2,4,5-triphenylimidazol-1-yl)acetamide 
• 1296625-79-0 N-[2-(4-methylphenylimino)-4-oxothiazolidin-3-yl]-2-(2,4,5-triphenylimidazol-1-yl)acetamide 
• 1296625-81-4 N-[2-(4-fluorophenylimino)-4-oxothiazolidin-3-yl]-2-(2,4,5-triphenylimidazol-1-yl)acetamide 
• 1296625-83-6 N-[2-(4-chlorophenylimino)-4-oxothiazolidin-3-yl]-2-(2,4,5-triphenylimidazol-1-yl)acetamide 

Relevant academic research and scientific papers

Synthesis of imidazole derivatives: Ester and hydrazide compounds with antioxidant activity using ionic liquid as an efficient catalyst

The pyrrolidinium hydrogen sulfate (PHS) was used as an excellent ionic liquid catalyst for the preparation of many imidazoles moiety, which have biologically application via one-pot multicomponent reaction. Imidazoles were afforded through the reaction o

Design and synthesis of some azole derivatives containing 2,4,5-triphenyl imidazole moiety as anti-inflammatory and antimicrobial agents

A series of azole derivatives (5a-d, 6a-d and 7a-d) have been synthesized from (2,4,5-triphenyl-imidazole-1-yl)-acetic acid hydrazide under various reaction conditions. Elemental analysis, IR, 1H NMR and mass spectral data confirmed the structure of the n

Microwave-assisted synthesis of 2,4,5-triphenyl-1h-imidazole containing schiff base derivatives with potential antioxidant and anticancer activities

2-(2,4,5-Triphenyl-1H-imidazol-1-yl)acetohydrazide (3) was utilized as key intermediate for the synthesis of some new Schiff bases 4a-k and 5 under reflux temperature as well as microwave irradiation. All the synthesized compounds were characterized by IR

Ultrasound-assisted synthesis of 2,5-dimethyl-N-substituted pyrroles catalyzed by uranyl nitrate hexahydrate

An efficient synthesis of different novel 2,5-dimethyl-N-substituted pyrrole derivatives by the Paal-Knorr condensation has been accomplished using uranyl nitrate hexahydrate as catalyst under soft conditions and ultrasonic irradiation. The synthesized compounds were confirmed through spectral characterization using IR, 1H NMR, 13C NMR and mass spectra.

Synthesis, characterization of some new five membered heterocycles based on imidazole moiety and their applications on therapeutics

Different imidazole derivatives were prepared by utilizing the intermediate 2-(2,4,5-triphenyl-1H-imidazol-1- yl)acetohydrazide (3) using microwave irradiation method besides the traditional ones. They were used for synthesis of some new derivatives of 2,5-disubstituted-1,3,4-oxadiazole, pyrazole, 2,5-dimethylpyrrole and nitrogen containing five membered rings. All the synthesized compounds were characterized by IR, 1H & 13C NMR and mass spectral data. The antibacterial, antifungal (MIC) and antioxidant activities were verified for all the synthesized compounds.

Substituted imidazole derivatives as novel cardiovascular agents

A series of novel substituted imidazole derivatives were synthesized and have been screened in vivo for their hypotensive and acute toxicity activities. Out of seventeen compounds eight compounds (2b, 2c, 3b, 3c, 3f, 4a, 4b and 4c) have shown good hypoten

Cardiovascular effects of novel imidazoline congeners

2-Aryl-4,5-bis(diphenyl)-1-(N-acetyl hydrazide)-1,3-imidazoline (IIb1- 4) was prepared by the reaction of ethyl chloro acetate and hydrazine hydrate with 2-Aryl-4,5-bis (diphenyl) - 1H - imidazoline (I a1-4), which on further substitution with aryl/heterocyclyl aldheyde gave 2-Aryl-4,5-his (diphenyl)- 1-(4-substituted hydrazone) -1,3 - imidazoline (III Ca-1). This was again cyclised to oxadiazole in the presence of ferric chloride and glacial acetic acid yielded 2-Aryl-4,5-bis(diphenyl)-1-(2-substituted-1,3,4-oxadizole)-1,3- imidazoline (IV da-i). These compounds were screened for hypotensive activity and an attempt were made to get the site of action of these compounds.