25513-92-2

Usage

Uses

Used in Pharmaceutical Industry:
ETHYL 3-METHYLPYRAZINE-2-CARBOXYLATE is used as a reactant for the preparation of pyrazines, which are important in the development of pharmaceutical compounds. These pyrazines can be utilized as building blocks for the synthesis of various drug molecules, contributing to the advancement of new therapeutic agents.
Used in Chemical Synthesis:
In the field of chemical synthesis, ETHYL 3-METHYLPYRAZINE-2-CARBOXYLATE is used as a reactant for the preparation of piperazinones and quinoxalines. These compounds have a wide range of applications, including their use as intermediates in the synthesis of various organic compounds, dyes, and pigments.
Used in Research and Development:
ETHYL 3-METHYLPYRAZINE-2-CARBOXYLATE is also used in research and development for the exploration of new synthetic routes and the development of novel compounds with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.

Upstream product

• 94127-05-6 ethyl 3-[(aminocarbonyl)diazenyl]but-2-enoate 
• 107-15-3 ethylenediamine 
• 95239-03-5 tert-butyl 2-(4-ethoxy-4-oxobut-2-en-2-yl)diazene-1-carboxylate 
• 64-17-5 ethanol 
• 41110-28-5 3-methylpyrazine-2-carboxylic acid 

Downstream Products

• 1383919-14-9 3-[2-chloro-4-methanesulfonyl-3-(3-methyl-4,5-dihydro-isoxazol-5-yl)-phenylmethanesulfonylmethyl]-pyrazine-2-carboxylic acid methyl ester 
• 1383919-13-8 3-[2-chloro-4-methanesulfonyl-3-(3-methyl-4,5-dihydro-isoxazol-5-yl)benzylsulfanylmethyl]-pyrazine-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Straightforward access to pyrazines, piperazinones, and quinoxalines by reactions of 1,2-diaza-1,3-butadienes with 1,2-diamines under solution, solvent-free, or solid-phase conditions

The preparation of tetrahydropyrazines, dihydropyrazines, pyrazines, piperazinones, and quinoxalines by 1,4-addition of 1,2-diamines to 1,2-diaza-1,3-butadienes bearing carboxylate, carboxamide, or phosphorylated groups at the terminal carbon and subseque

HERBICIDAL COMPOUNDS

The present invention relates to 6,6-dioxo-6-thia-1,4-diaza-naphthalene derivatives of formula (I) where R1, R2, R3a, R3b, R4 and R5 are as defined in claim 1; or a salt or N-oxide thereof.

Dipeptidyl peptidase-IV inhibitors

The invention provides compounds of Formula (I) or prodrugs thereof, or pharmaceutically acceptable salts of said compounds or prodrugs, or solvates of said compounds, prodrugs or salts, wherein A, N, X and R1 are as defined herein; pharmaceutical compositions thereof; and methods of using the pharmaceutical compositions for the treatment of diseases, including Type 2 diabetes, Type 1 diabetes, impaired glucose tolerance, hyperglycemia, metabolic syndrome (syndrome X and/or insulin resistance syndrome), glucosuria, metabolic acidosis, arthritis, cataracts, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic cardiomyopathy, obesity, conditions exacerbated by obesity, hypertension, hyperlipidemia, atherosclerosis, osteoporosis, osteopenia, frailty, bone loss, bone fracture, acute coronary syndrome, short stature due to growth hormone deficiency, infertility due to polycystic ovary syndrome, anxiety, depression, insomnia, chronic fatigue, epilepsy, eating disorders, chronic pain, alcohol addiction, diseases associated with intestinal motility, ulcers, irritable bowel syndrome, inflammatory bowel syndrome; short bowel syndrome; and the prevention of disease progression in Type 2 diabetes.

Different behavior of the reaction between 1,2-diaza-1,3-butadienes and 1,2-diamines under solvent or solvent-free conditions

New piperazinones are obtained in satisfactory yields by reaction of 1,2-diaza-1,3-butadienes with 1,2-diamines under solvent-free conditions. In polar solvents, the same reagents give rise to interesting dihydropyrazines and then to pyrazines by oxidatio