25529-25-3

Basic information

• Product Name: L-Valine, N-[(phenylmethoxy)carbonyl]-, pentafluorophenyl ester
• CAS NO: 25529-25-3
• Molecular Formula: C19H16F5NO4
• Molecular Weight: 417.332
• Mol File: 25529-25-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Valine, N-[(phenylmethoxy)carbonyl]-, pentafluorophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Valine, N-[(phenylmethoxy)carbonyl]-, pentafluorophenyl ester(25529-25-3)
• EPA Substance Registry System: L-Valine, N-[(phenylmethoxy)carbonyl]-, pentafluorophenyl ester(25529-25-3)

Safety Data

• Hazardous Substances Data: 25529-25-3(Hazardous Substances Data)

Upstream product

• 14533-84-7 pentafluorophenyl trifloroacetate 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 

Downstream Products

• 1134849-47-0 Z-Val-Tyr-Pro-Asp-Lys(Boc)-OH 
• 1134849-50-5 Z-Val-Val-Tyr-Pro-Asp-Lys(Boc)-OH 
• 913971-44-5 benzyl (S)-3-methyl-1-oxo-1-(2-oxooxazolidin-3-yl)butan-2-ylcarbamate 
• 22221-75-6 N-(N-benzyloxycarbonyl-L-valyl)-glycine 
• 19542-51-9 N-benzyloxycarbonyl-L-valyl-L-phenylalanine 
• 13409-17-1 N-benzyloxycarbonyl-L-valyl-γ-tert-butyl-L-glutamyl-L-alanine methyl ester 

Relevant articles and documents

Novel, Chiral, and Enantiopure C2-Symmetric Thioureas Promote Asymmetric Protio-Pictet-Spengler Reactions by Anion-Binding Catalysis

Although anion-binding processes are well-known for their crucial role in molecular recognition, they have only recently been utilized for catalysis. Herein, a new class of chiral, enantiopure C2-symmetrical thioureas that, in combination with 4-methoxybenzoic acid, promotes the enantioselective protio-Pictet-Spengler reaction to provide unprotected tetrahydro-β-carbolines in good yields (40–93 %) and moderate-to-high enantioselectivities (34–95 % ee) in one step from tryptamine and aldehyde derivatives is described. The formation of a chiral catalyst-anion complex was explored by 1H NMR.