13409-17-1Relevant academic research and scientific papers
Macrocyclization of Peptide Side Chains by the Ugi Reaction: Achieving Peptide Folding and Exocyclic N-Functionalization in One Shot
Vasco, Aldrin V.,Pérez, Carlos S.,Morales, Fidel E.,Garay, Hilda E.,Vasilev, Dimitar,Gavín, José A.,Wessjohann, Ludger A.,Rivera, Daniel G.
, p. 6697 - 6707 (2015)
The cyclization of peptide side chains has been traditionally used to either induce or stabilize secondary structures (β-strands, helices, reverse turns) in short peptide sequences. So far, classic peptide coupling, nucleophilic substitution, olefin metat
