25532-76-7 Usage
Uses
Used in Pharmaceutical Industry:
(2'S)-2',3',6',7'-Tetrahydro-2'β-(hydroxymethyl)-2',4',6'-trimethylspiro[cyclopropane-1,5'-[5H]indene]-3'α,6'β,7'α-triol is used as a potential pharmaceutical agent for its unique structural features. The presence of multiple hydroxyl and methyl groups, along with the cyclopropane-1,5'-[5H]indene core, may contribute to its biological activity, making it a candidate for further exploration in drug development.
Used in Chemical Research:
In the field of chemical research, (2'S)-2',3',6',7'-Tetrahydro-2'β-(hydroxymethyl)-2',4',6'-trimethylspiro[cyclopropane-1,5'-[5H]indene]-3'α,6'β,7'α-triol serves as a subject of study for understanding the synthesis and properties of complex spiro compounds. Its unique structure may offer insights into the development of new synthetic pathways and the exploration of novel chemical reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 25532-76-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,5,3 and 2 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 25532-76:
(7*2)+(6*5)+(5*5)+(4*3)+(3*2)+(2*7)+(1*6)=107
107 % 10 = 7
So 25532-76-7 is a valid CAS Registry Number.
25532-76-7Relevant academic research and scientific papers
Structure-Activity Relationships of Illudins: Analogs with Improved Therapeutic Index
McMorris, Trevor C.,Kelner, Michael J.,Wang, Wen,Estes, Leita A.,Montoya, Mark A.,Taetle, Raymond
, p. 6876 - 6883 (2007/10/02)
Illudin S and M are extremely toxic sesquiterpenes produced by Omphalotus illudens.At low pH they behave as bifunctional alkylating agents, but at physiological pH they do not react with oxygen or nitrogen nucleophiles.Illudins react spontaneously with sulfur nucleophiles, gluthathione or cysteine, at or slightly below pH 7, and toxicity to HL 60 cells can be modulated by altering glutathione levels in cells.Analogs of illudin M, e.g. the deoxy and, particularly, the dehydro derivatives, are less reactive to thiols and correspondingly less toxic to HL 60 cells than the parent compound.Dehydroilludin M has been found to be quite effective at inhibiting tumor growth in vivo at doses well tolerated at athymic nude mice.
