25546-09-2

Usage

InChI:InChI=1/C9H11ClN2O2/c1-12(2)9(14)11-7-4-3-6(10)5-8(7)13/h3-5,13H,1-2H3,(H,11,14)

Upstream product

• 905303-92-6 acetic acid 5-chloro-2-(3,3-dimethyl-ureido)-phenyl ester 
• 905303-91-5 acetic acid 5-chloro-2-isocyanato-phenyl ester 
• 905303-89-1 4-chloro-2-hydroxy-benzoyl azide 
• 905303-90-4 acetic acid 2-azidocarbonyl-5-chloro-phenyl ester 
• 22717-55-1 methyl 4-chloro-2-hydroxybenzoate 
• 65920-15-2 4-Chloro-2-hydroxy-benzoic acid hydrazide 
• 150-68-5 monuron 

Relevant academic research and scientific papers

Kinetic and analytical study of the photo-induced degradation of monuron by nitrates and nitrites under irradiation or in the dark

The photo-induced transformation of monuron (3-(4-chlorophenyl)-1,1 dimethylurea) was investigated in an aqueous solution containing nitrates and nitrites at 310 nm and 365 nm, respectively. In both NO3- and NO2-/sup

Identification and formation pathway of laccase-mediated oxidation products formed from hydroxyphenylureas

Hydroxyphenylureas are the first main metabolites formed in the environment from pesticide and biocide urea compounds. Because fungi release potent exocellular oxidases, we studied the ability of laccases produced by the white rot fungus, T. versicolor, to catalyze in vitro the transformation of five hydroxyphenylureas, to identify transformation pathways and mechanisms. Our results establish that the pH of the reaction has a strong influence on both the kinetics of the reaction and the nature of the transformation products. Structural characterization by spectroscopic methods (NMR, mass spectrometry) of eleven transformation products shows that laccase oxidizes the substrates to quinones or to polyaromatic oligomers. Slightly acidic conditions favor the formation of quinones as final transformation products. In contrast, at pH 5-6, the quinones further react with the remaining substrate in solution to give hetero-oligomers via carbon-carbon or carbon-oxygen bond formation. A reaction pathway is proposed for each of the identified products. These results demonstrate that fungal laccases could assist the transformation of hydroxyphenylureas.