25564-63-0

Upstream product

• 1258546-53-0 C₁₄H₁₅NO₄S 
• 1258546-55-2 C₁₄H₁₅NO₄S 
• 57-41-0 phenythoin 
• 75406-50-7 1,1,1-trimethyl-2-(1-phenylethylidene)hydrazinium iodide 
• 7492-91-3 methyl N-(2-iodo-1,1-diphenylethane)carbamate 

Downstream Products

• 113009-77-1 bis(2,2-diphenyl-1-aziridinyl)phosphinic amide 
• 113009-74-8 ethyl bis(2,2-diphenyl-1-aziridinyl)phosphinate 
• 39830-44-9 (S)-(+)-1-chloro-2,2-diphenylaziridine 
• 79258-01-8 (R)-(-)-1-Chloro-2,2-diphenylaziridine 
• 69681-77-2 2-Fluoro-2,2-diphenylethylamine 
• 39830-44-9 1-chloro-2,2-diphenyl-aziridine 

Relevant academic research and scientific papers

Aziridines in one step from hydantoins via Red-Al mediated ring-contraction

We have developed a new method to synthesize aziridines from their corresponding hydantoins in one step using an excess of Red-Al overnight in refluxing toluene. This allows direct access to N-H aziridines without the need for protecting group strategies.

An improved and mild wenker synthesis of aziridines

The conventional Wenker synthesis of aziridines from vicinal amino alcohols has been modified by employing mild reaction conditions. Amino alcohols were converted into their hydrogen sulfates with chlorosulfonic acid. The sulfates were cyclized with sodium hydroxide, and even with non-nucleophilic sodium carbonate. The current, improved method extends the scope of the typical Wenker synthesis and is applicable to unstable amino alcohols in hot sulfuric acid and to unstable sulfates which favor elimination and hydroxide displacement in the presence of strong base. Georg Thieme Verlag Stuttgart.

Synthesis, Molecular Symmetry, and Chemical Reactivity of C-Aryl-Substituted Phosphoraziridines

P,P-Bis- and P,P,P-tris(1-aziridinyl)phosphoramides containing aryl-substituted aziridine moieties, including para-substituted 2-phenylaziridines, an optically active aziridine, and all the possible C-aryl regioisomers of diphenylaziridine were prepared b

Synthese d'aziridines: Action d'organomagnesiens sur des iodures de N,N,N-trimethylhydrazonium

The reaction of Grignard reagents with N,N,N-trimethyl hydrazonium iodides provides a good method for the synthesis of secondary aziridines and specialy for aziridines 17a, b, 22, 24 and 25 which cannot be prepared by the Hoch-Campbell procedure (1) (reac