2558-18-1

Basic information

• Product Name: 3-[(4-Fluorophenyl)methylene]phthalide
• Synonyms: 3-[(4-fluorophenyl)methylene]phthalide;3-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-3H-isobenzofuran-1-one;4-FLUOROBENZYLIDENEPHTHALIDE;4-Fluorobenzalphthalide;3-(4-FLURFENYL)METYLIDN FTALID;(3E)-3-[(4-Fluorophenyl)methylidene]-2-benzofuran-1-one;3-(4-Fluorobenzylidene)-1(3H)-isobenzofuranone;3-(4-Fluorobenzylidene)phthalide
• CAS NO: 2558-18-1
• Molecular Formula: C₁₅H₉FO₂
• Molecular Weight: 240.23
• EINECS: 219-877-8
• Mol File: 2558-18-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: 140-142°C
• Boiling Point: 372.3°Cat760mmHg
• Flash Point: 172.9°C
• Appearance: /
• Density: 1.349g/cm³
• Vapor Pressure: 9.72E-06mmHg at 25°C
• Refractive Index: 1.665
• CAS DataBase Reference: 3-[(4-Fluorophenyl)methylene]phthalide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(4-Fluorophenyl)methylene]phthalide(2558-18-1)
• EPA Substance Registry System: 3-[(4-Fluorophenyl)methylene]phthalide(2558-18-1)

Safety Data

• Hazardous Substances Data: 2558-18-1(Hazardous Substances Data)

Usage

General Description

3-[(4-Fluorophenyl)methylene]phthalide is a chemical compound known for its use in various applications, including as a dye intermediate and in the synthesis of pharmaceuticals. It is a phthalide derivative with a 4-fluorophenyl group attached to the carbon atom, and it is commonly used as a building block in organic synthesis. 3-[(4-Fluorophenyl)methylene]phthalide has shown potential as a drug candidate due to its pharmacological properties, such as its anti-inflammatory and anticancer effects. Additionally, 3-[(4-Fluorophenyl)methylene]phthalide has been studied for its potential use in the treatment of neurological disorders and as a fluorescent probe for detecting certain biological molecules. Overall, this compound has garnered attention for its diverse applications in the fields of chemistry and medicine.

InChI:InChI=1/C15H9FO2/c16-11-7-5-10(6-8-11)9-14-12-3-1-2-4-13(12)15(17)18-14/h1-9H/b14-9+

Upstream product

• 85-44-9 phthalic anhydride 
• 405-50-5 p-Fluorophenylacetic acid 

Downstream Products

• 1416901-08-0 diethyl 2-[4-fluorobenzyl-1-oxo-2(1H)-phthalazinyl]-3-(1,1,1-triphenyl-λ⁵-phosphanylidene)succinate 
• 1416901-07-9 dimethyl 2-[4-(4-fluorobenzyl-1-oxo-2(1H)-phthalazinyl)]-3-(1,1,1-triphenyl-λ⁵-phosphanylidene)succinate 
• 120359-17-3 4-(4-fluorobenzyl)-1(2H)-phthalazinone 
• 957-56-2 fluindione