2558-28-3 Usage
General Description
E-ALPHA-(4-FLUOROPHENYL)CINNAMONITRILE, also known as 4-(4-Fluorophenyl)-2-(E)-pentenenitrile, is a chemical compound that belongs to the class of cinnamic nitriles. It is a colorless to pale yellow liquid with a strong, sweet, floral odor. E-ALPHA-(4-FLUOROPHENYL)CINNAMONITRILE& is commonly used in the manufacturing of fragrances for perfumes and cosmetics due to its pleasant scent. It is also used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. Additionally, E-ALPHA-(4-FLUOROPHENYL)CINNAMONITRILE has potential applications in the production of agrochemicals, polymer additives, and other industrial products.
Check Digit Verification of cas no
The CAS Registry Mumber 2558-28-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,5 and 8 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2558-28:
(6*2)+(5*5)+(4*5)+(3*8)+(2*2)+(1*8)=93
93 % 10 = 3
So 2558-28-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H10FN/c16-15-8-6-13(7-9-15)14(11-17)10-12-4-2-1-3-5-12/h1-10H/b14-10+
2558-28-3Relevant articles and documents
Switchable Cobalt-Catalyzed α-Olefination and α-Alkylation of Nitriles with Primary Alcohols
Paudel, Keshav,Xu, Shi,Ding, Keying
supporting information, p. 5028 - 5032 (2021/07/19)
The first switchable α-olefination and α-alkylation of nitriles with primary alcohols catalyzed by a well-defined base transition-metal Co complex was presented. A broad variety of nitriles and primary alcohols are selectively and efficiently converted to the corresponding products by this method. It is noteworthy that the transformation is environmentally benign and atom efficient with H2and H2O being the sole byproducts.
Heteroaryl β-tetralin ureas as novel antagonists of human TRPV1
Jetter, Michele C.,Youngman, Mark A.,McNally, James J.,McDonnell, Mark E.,Zhang, Sui-Po,Dubin, Adrienne E.,Nasser, Nadia,Codd, Ellen E.,Flores, Christopher M.,Dax, Scott L.
, p. 6160 - 6163 (2008/03/18)
We report on a series of α-substituted-β-tetralin-derived and related phenethyl-based isoquinolinyl and hydroxynaphthyl ureas as potent antagonists of the human TRPV1 receptor. The synthesis and Structure-activity relationships (SAR) of the series are described.
