255826-65-4

Upstream product

• 123-73-9 trans-Crotonaldehyde 
• 104-94-9 4-methoxy-aniline 
• 7757-82-6 sodium sulfate 
• 123-73-9 crotonaldehyde 

Downstream Products

• 101535-98-2 cis-3-methoxy-1-(4-methoxyphenyl)-4-(prop-1-enyl)azetidin-2-one 

Relevant academic research and scientific papers

Promoting Frustrated Lewis Pairs for Heterogeneous Chemoselective Hydrogenation via the Tailored Pore Environment within Metal–Organic Frameworks

Frustrated Lewis pairs (FLPs) have recently been advanced as efficient metal-free catalysts for catalytic hydrogenation, but their performance in chemoselective hydrogenation, particularly in heterogeneous systems, has not yet been achieved. Herein, we demonstrate that, via tailoring the pore environment within metal–organic frameworks (MOFs), FLPs not only can be stabilized but also can develop interesting performance in the chemoselective hydrogenation of α,β-unsaturated organic compounds, which cannot be achieved with FLPs in a homogeneous system. Using hydrogen gas under moderate pressure, the FLP anchored within a MOF that features open metal sites and hydroxy groups on the pore walls can serve as a highly efficient heterogeneous catalyst to selectively reduce the imine bond in α,β-unsaturated imine substrates to afford unsaturated amine compounds.

Taxoid anti-tumor agents and pharmaceutical compositions thereof

Pharmaceutical compositions, methods of administration, and methods of treatment of cancer with new generation taxoids, of formulas (I) and (II), and derivatives thereof, are described:

Taxoid anti-tumor agents and pharmaceutical compositions thereof

Pharmaceutical compositions, methods of administration, and methods of treatment of cancer with new generation taxoids, of formulas (I) and (II), and derivatives thereof, are described: 1

Taxoid anti-tumor agents, pharmaceutical compositions, and treatment methods

A taxoid of formula (7), a method for making the taxoid, a pharmaceutical composition containing the taxoid, and a method for treating tumors by administering the taxoid: whereinR1 is a branched or unbranched C3-C5 alkyl o

Taxoid anti-tumor agents and pharmaceutical compositions thereof

This invention relates to a taxoid of the formula (I): STR1 wherein R1 is a C3 -C5 alkyl or alkenyl or trifluoromethyl radical; R2 is a C3 -C5 branched alkyl radical; R3 and Rsu

Syntheses and structure-activity relationships of taxoids derived from 14β-hydroxy-10-deacetylbaccatin III

A series of new taxoids derived from 14β-hydroxy-10-deacetylbaccatin III was synthesized by means of the β-lactam synthon method. Most of the new taxoids thus synthesized possess excellent cytotoxicity against human ovarian (A121), non-small-cell lung (A5

Studies on Lactams. Part 74. An Approach to the Total Synthesis of Amino Sugars via β-Lactams

Convenient intermediates for mono- and di-amino sugars related to antibiotics can be prepared in a stereocontrolled fashion by the rearrangement of 3,4-disubstituted azetidin-2-ones which in turn can be synthesized by stereoselective annelation of certain