7757-82-6

Basic information

• Product Name: Sodium sulfate
• Synonyms: anhydrous sodium sulphate;sodium carbonate powder;anhydrous sodium carbonate;sodium formate powder;sodium formaite;Sodium sulfate;sodium Sulphate;solid sodium carbonate;sodium carbonate solution;sodium formiate;anhydrous sodium formate
• CAS NO: 7757-82-6
• Molecular Formula: 2Na*O₄S
• Molecular Weight: 142.04214
• EINECS: 231-820-9
• Mol File: 7757-82-6.mol
• Article Data: 1180

Chemical Properties

• Melting Point: 884℃/884℃(lit.)
• Boiling Point: 330 °C at 760 mmHg
• Appearance: white crystals or powder
• Density: 2.68 g/mL at 25 °C(lit.)
• Vapor Pressure: 3.35E-05mmHg at 25°C
• Water Solubility: 18.5 mg/L
• CAS DataBase Reference: Sodium sulfate(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium sulfate(7757-82-6)
• EPA Substance Registry System: Sodium sulfate(7757-82-6)

Safety Data

• Hazard Codes: Xi:Irritant
• Statements: R36:Irritating to eyes.
• Safety Statements: S24/25:
• Hazardous Substances Data: 7757-82-6(Hazardous Substances Data)

Usage

InChI:InChI=1/2Na.H2O4S/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2

Synthetic route

sodium sulfide → sodium sulfate (7757-82-6)

Conditions	Yield
With sulfur dioxide byproducts: S2; 600°C;	99.98%
With SO2 byproducts: S2; 600°C;	99.98%
With sulfur dioxide byproducts: S2; 500°C;	66.82%

ammonium sulfate + sodium chloride (7647-14-5) → sodium sulfate (7757-82-6)

Conditions	Yield
In not given reaction of a soln. of (NH4)2SO4 and an excess of common salt;;	98%
In not given reaction of a soln. of (NH4)2SO4 and an excess of common salt;;	98%
With ammonium chloride In neat (no solvent) metathesis of (NH4)2SO4 with NaCl in presence of NH4Cl at 600 °C;;

sodium hypoiodite (22468-64-0) + sodium thiosulfate → sodium sulfate (7757-82-6)

Conditions	Yield
In not given in very weakly acidic soln.;	90%
In not given in very weakly acidic soln.;	90%

sodium hydrogen sulfate (7681-38-1) + sodium chloride (7647-14-5) → hydrogenchloride (7647-01-0) + sodium sulfate (7757-82-6)

Conditions	Yield
In neat (no solvent) at 200 - 450°C;;	A 90% B n/a
In sulfuric acid

mirabilite → water (7732-18-5) + sodium sulfate (7757-82-6)

Conditions	Yield
In water by salting-out: addn. of a hot satd. NaCl-soln. at 82°C;;	A n/a B 90%
In melt High Pressure; dehydration in autoclaves: melting at 60°C, separation of pptd. Na2SO4, heating of mother-liquor to 280-300°C, further heating in an autoclave to 370°C, pptn.;; dry product;;	A n/a B >99
dehydration with CBr4 or CBr4 with 10% CCl4 at about 100°C;;

Glauber's salt → sodium sulfate (7757-82-6)

Conditions	Yield
In neat (no solvent) byproducts: H2O; dehydration of Glauber's salt; crystallization below 33. degree.C by additon addition of common salt or magnesium sulfate;;	90%
In neat (no solvent) byproducts: H2O; dehydration of Glauber's salt; crystallization below 33. degree.C by additon addition of common salt or magnesium sulfate;;	90%
In neat (no solvent) byproducts: H2O; dehydration of Glauber's salt at 100 °C;;	46%

sodium hypochlorite (7681-52-9) + sodium thiosulfate → sodium tetrathionate + sodium sulfate (7757-82-6)

Conditions	Yield
In not given in very weakly acidic soln.;	A 20% B 80%
In not given in very weakly acidic soln.;	A 20% B 80%

sodium sulfide + calcium(II) nitrate (13477-34-4) + sodium sulfite (7757-83-7) → calcium sulfate + sodium sulfate (7757-82-6) + sodium nitrite (7632-00-0)

Conditions	Yield
In neat (no solvent) formation at heating under glowing;;	A n/a B n/a C 60%

sulfuric acid (7664-93-9) + potassium hydroxide + sodium hydroxide (1310-73-2) → tripotassium sodium bis(sulfate) + sodium sulfate (7757-82-6)

Conditions	Yield
In water aq. soln. of KOH and NaOH (mol ratio 3:1) was treated with concd. H2SO4 until pH 3; pptn. with MeOH;	A 60% B 40%

ammonium sulfate + sodium isocyanate (917-61-3) → sodium sulfate (7757-82-6) + urea (57-13-6)

Conditions	Yield
In not given excess of (NH4)2SO4;	A n/a B 32%

sulfuric acid (7664-93-9) + sodium nitrite (7632-00-0) → sodium nitrate (7631-99-4) + nitrogen(II) oxide (10102-43-9) + sodium sulfate (7757-82-6) + dinitrogen monoxide (10024-97-2)

Conditions	Yield
byproducts: H2O, N2; NO collection, storing over dil. sodium hydroxide soln. (NO2 impurity elimination);	A n/a B n/a C n/a D 1%

Sodium thiosulfate pentahydrate → sodium sulfate (7757-82-6) + sodium sulfite (7757-83-7)

Conditions	Yield
standing for 2.5 months;	A n/a B 0.015%
With oxygen In neat (no solvent) oxidation at 150°C;;
standing for 2.5 months;	A n/a B 0.015%

sodium sulfite (7757-83-7) → sodium dithionite + hydrogen (1333-74-0) + sodium sulfate (7757-82-6)

Conditions	Yield
In water Photoelectrolysis;

sodium catecholate (20244-21-7, 34789-97-4, 51818-64-5, 7664-47-3) + sodium phenoxide (139-02-6) + disodium salt of hydroquinone (7664-46-2, 17200-59-8, 30008-10-7, 51818-63-4) → benzene-1,2-diol (120-80-9) + sodium sulfate (7757-82-6) + hydroquinone (123-31-9) + phenol (108-95-2)

Conditions	Yield
With sulfuric acid In water Purification / work up; Industry scale;

Iodine monochloride (7790-99-0) + sodium sulfate (7757-82-6) → sodium chloride (7647-14-5)

Conditions	Yield
evaporated, with excess of ICl;	100%
evaporated, with excess of ICl;	100%

sulfur trioxide (7446-11-9) + sodium sulfate (7757-82-6) → sodium pyrosulfate

Conditions	Yield
SO3 in excess, 10-15 min, closed vessel 450°C;	100%
react. of Na2SO4 with SO3 at ambient temp.;; substance with Na2S2O7 and unchanged Na2SO4 obtained;;
In neat (no solvent) react. of Na2SO4 with an excess of SO3 above 150°C;;

aluminum oxide (1333-84-2, 1344-28-1) + sodium sulfate (7757-82-6) → sodium aluminate (1302-42-7)

Conditions	Yield
excess of Al2O3; at yellow heat in air;	100%
at 1300°C, 3h;
at white heat;	0%

potassium sulfate + sodium sulfate (7757-82-6) → tripotassium sodium bis(sulfate)

Conditions	Yield
In water salt deposited from aq. soln. of 3 mol K2SO4 and 1 mol Na2SO4 by addition of methanol;	100%
In water aq. soln. of 3 mol K2SO4 and 1 mol Na2SO4 controlled at pH 3; salt deposited by addition of methanol; product contains 20 % K2SO4;	80%
In water aq. soln. of K2SO4 and Na2SO4 (molar ratio 3:1) was concd. by rotary evaporator; product contains 50% K2SO4;	50%
In melt heating (50°C above melting point of constituents, 1 h), quenching (room temp.); powder XRD;
In water molar ratio 3:1 or 1:1, slow evapn. at room temp. and at 40°C;;

tert-butyl methyl ether (1634-04-4) + cesium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] dihydrate + sodium sulfate (7757-82-6) → sodium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] dihydrate methyl tert-butyl ether

Conditions	Yield
Stage #1: sodium sulfate With aluminum(III) sulphate octadecahydrate In water at 20℃; for 0.5h; Stage #2: cesium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] dihydrate With cesium chloride In water at 20℃; for 30h; Stage #3: tert-butyl methyl ether In acetonitrile	100%

sodium sulfate (7757-82-6) + (+/-)-5-(tert-butyl)-2,3-dihydro-1H-indene-2-methanol (173445-30-2) → (+/-)-5-(tert-butyl)-2,3-dihydro-1H-indene-1-ethanol (769196-23-8)

Conditions	Yield
With sodium hydroxide; LiAlH4 In ethyl acetate	99%

[Ni(RRSS)-CH2(CH2NHCH2CH2NHCH2)2NC3N3(NH2)2](2+) (461645-27-2, 462103-94-2) + sodium sulfate (7757-82-6) → [Ni(RRSS)-CH2(CH2NHCH2CH2NHCH2)2NC3N3H(NH2)2](ClO4)SO4*3.5H2O

Conditions	Yield
In hydrogenchloride Ni-complex was recrystd. from 2 M HCl; elem. anal.;	99%

6-bromohexanoic acid (4224-70-8) + toluene-4-sulfonic acid (104-15-4) + sodium sulfate (7757-82-6) → benzyl 6-bromohexanoate (78277-26-6)

Conditions	Yield
With sodium hydrogencarbonate; benzyl alcohol In water; toluene	99%

toluene-4-sulfonic acid (104-15-4) + sodium sulfate (7757-82-6) → Benzyl chloroacetate (140-18-1)

Conditions	Yield
With sodium hydrogencarbonate; chloroacetic acid; benzyl alcohol In water; toluene	99%

1,4-diaza-bicyclo[2.2.2]octane (280-57-9) + terephthalic acid (100-21-0) + sodium sulfate (7757-82-6) + zinc(II) oxide → [(zinc)2(terephthalate)2(1,4-diazabicyclo[2.2.2]octane)]*(x)Na2SO4 [Zn2(C6H4(COO)2)2(N2(C2H4)3)]*99Na2SO4, hexagonal

Conditions	Yield
With DMF In solid mixt. of ZnO, C6H4(COOH)2, N2(C2H4)3 (in stoich. ratio 1:1:0.5), Na2SO4 (12% weight fraction of solid reagents) and DMF ground at room temp. for30 min; detd. by XRD;	99%

fructone (6413-10-1) + sodium sulfate (7757-82-6) → 2-(2-methyl-1,3-dioxolan-2-yl)ethanol (5754-32-5)

Conditions	Yield
In diethyl ether	97%

carbon monoxide (201230-82-2) + water (7732-18-5) + sodium sulfate (7757-82-6) → sodium carbonate (497-19-8)

Conditions	Yield
iron(III) oxide In neat (no solvent) passing a mixture of CO/H2O-vapor over powdered Na2SO4 at 660°C; partial pressure of H2O: 0.3 at, catalyst: Fe2O3 in form of a Fe(NO3)2-soln.;; 85-92% Na2CO3;;	97%
With catalyst: Fe2O3 and Sb2O5 or Fe2O3 and Sb2O4 or; Fe2O3 and As2O5 In neat (no solvent) passing a mixture of CO/H2O-vapor (CO from passing air through hot charcoal) over Na2SO4; partial pressure of H2O: 0.4 at, gas, containing 14.6% CO, is applied in 1.5-fold excess; catalyst: mixture of Fe2O3 and Sb2O5, Sb2O4 or As2O5;; 88.5% Na2CO3;;	93.8%
With catalyst: Fe2O3 and Sb2O5 or Fe2O3 and Sb2O4 or; Fe2O3 and As2O5 In neat (no solvent) passing a mixture of CO/H2O-vapor (CO from passing air through hot charcoal) over Na2SO4, partial pressure of H2O: 0.4 at, catalyst :mixture of Fe2O3 and Sb2O5, Sb2O4 or As2O5;; 91.3-95.6% Na2CO3;;	94-97.6

3-Methyl 5-ethyl 4-(4-fluorophenyl)-6-isopropyl-(1H)-pyrid-2-one-3,5-dicarboxylate (130318-26-2) + sodium sulfate (7757-82-6) + methyl iodide (74-88-4) → 3-Methyl 5-ethyl 4-(4-fluorophenyl)-6-isopropyl-2-methoxy-pyridine-3,5-dicarboxylate (156819-08-8)

Conditions	Yield
In N-methyl-acetamide; water	95.2%

3-Methyl 5-ethyl 4-(4-fluorophenyl)-6-isopropyl-(1H)-pyrid-2-one-3,5-dicarboxylate (130318-26-2) + sodium sulfate (7757-82-6) + methyl iodide (74-88-4) → 3-Methyl5-ethyl4-(4-fluorophenyl)-6-isopropyl-1-methyl-pyrid-2-one-3,5-dicarboxylate (130318-27-3)

Conditions	Yield
In N-methyl-acetamide; water	95.2%

3-(Dimethylaminomethyl)indole (87-52-5) + 2-nitrobutane (600-24-8, 116783-22-3) + sodium sulfate (7757-82-6) + dimethyl sulfate (77-78-1) → 3-(2-methyl-2-nitro-butyl)-indole (52669-52-0) + 1-indol-3-ylmethyl-1-methyl-propylamine (52577-44-3)

Conditions	Yield
With sodium In ethanol	A n/a B 95%

sodium sulfate (7757-82-6) → sodium phosphate

Conditions	Yield
With pyrographite In melt 1 part ferro-phosphorus, 2 parts Na2SO4, 0.06 wt.-parts carbon (or reducing atmosphere);;	95%
With phosphorite; pyrographite In neat (no solvent) 65 parts sulfate, 25 parts carbon, 100 parts phosphorite, 700°C, 60min, diminshed yield at longer reaction times;;	28.9%
With ferro-phosphorus In melt P-content of ferro-phosphorus >24%: addn. of ferro-phosphorus to molten Na2SO4, fluxing agent: CaF2;;

sulfur dioxide (7446-09-5) + water (7732-18-5) + sodium sulfate (7757-82-6) → sodium hydrogensulfite

Conditions	Yield
With calcium hydroxide In water satn. of Ca(OH)2 and Na2SO4 in H2O with SO2 at 30-35°C, 4h;; aq. soln. of NaHSO3 with 22.5% SO2;;	95%
With calcium carbonate In water treatment of powdered CaCO3 in Na2SO4-soln. with SO2, cyclic process;;
With calcium hydroxide In water byproducts: CaSO4; continuous formation of CaSO4 and NaHSO3 at constant pH;;

water (7732-18-5) + dibenzyltin(IV) dichloride (3002-01-5) + sodium sulfate (7757-82-6) → (((C6H5CH2)10(SnO)3(SnOH)2)SO4)2*4H2O

Conditions	Yield
In ethanol; water soln. of Sn compd. and Na2SO4 (molar ratio 1:1) in EtOH (95%) stirred at60°C for 24 h; filtered; filtrate evapd.; solid recrystd. from EtOH; elem. anal.;	95%

F6Ti(2-)*2H3N*2H(1+) + water (7732-18-5) + sodium fluoride + sodium sulfate (7757-82-6) → F6Ti(2-)*3Na(1+)*H3N*H2O*O4S(2-)*H(1+)

Conditions	Yield
at 210℃; for 96h; Autoclave; High pressure; Sealed tube;	95%

1H-imidazole (288-32-4) + 1-Hydroxy-3-butanone (590-90-9) + sodium sulfate (7757-82-6) + tert-butylchlorodiphenylsilane (58479-61-1) → 4-tert.Butyldiphenylsiloxybutan-2-one

Conditions	Yield
In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane	94%

sodium sulfate (7757-82-6) → sodium sulfite (7757-83-7)

Conditions	Yield
With pyrographite In neat (no solvent) redn., 750°C, diameter of C-particels about 0.4mm, 30min;;	93%
In neat (no solvent) byproducts: SO2; heating of Na2SO4 in under exclusion of air; evolution of SO2;;
With pyrographite In neat (no solvent) redn., coating of react.-vessel: forsterite;;
With pyrographite In melt melting with sand and coal;;

1H-imidazole (288-32-4) + methanol (67-56-1) + Nb6(14+)*14Cl(1-)*8H2O=(Nb6Cl12)Cl2(H2O)4*4H2O (12133-87-8) + sodium sulfate (7757-82-6) → [Nb6Cl12(1H-imidazole)6](SO4)·2(1H-imidazole)·CH3OH

Conditions	Yield
at 40℃; for 48h;	93%

lithium aluminium tetrahydride (16853-85-3) + 4-Phenoxyacetessigsaeure-ethylester (41051-18-7) + sodium sulfate (7757-82-6) → 4-phenoxybutane 1,3-diol

Conditions	Yield
In 1,2,3,4-tetrahydropyrimidine; diethyl ether; chloroform-d1; Petroleum ether	92%

4-fluoro-3-phenoxybenzaldehyde (68359-57-9) + permethric acid chloride (52314-67-7) + sodium sulfate (7757-82-6) → 3'-phenoxy-4'-fluoro-benzyl 2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropane-carboxylate (68359-33-1)

Conditions	Yield
In water; ethyl acetate	91.5%

methylbenzene ether + ethyl (4-fluorophenyl)5-benzoxazole acetate + sodium sulfate (7757-82-6) + oxalic acid diethyl ester (95-92-1) → ethyl 2(4-fluorophenyl)5-benzoxazole oxalacetate

Conditions	Yield
With sodium methylate In toluene	91%

sodium sulfate (7757-82-6) → sulfuric acid (7664-93-9) + sodium hydroxide (1310-73-2)

Conditions	Yield
In water Electrolysis; formation of PbSO4 on Pb-anode; electrolysis of PbSO4;	A 91% B 91%
With H2O Electrolysis;
In water Electrolysis;

Upstream product

• 141-53-7 Sodium formate 
• 77-78-1 Dimethyl sulfate 
• 7727-73-3 SODIUM SULFATE DECAHYDRATE 
• 7647-14-5 Sodium chloride 
• 13767-89-0 GLAUBERITE 

Downstream Products

• 38220-75-6 1-(5-BROMO-1-BENZOFURAN-2-YL)ETHANONE 
• 3734-67-6 ACID RED 1 
• 72-57-1 Direct Blue 14 
• 73963-72-1 Cilostazol 
• 13484-37-2 1-(2-PHENOXYETHYL)-PIPERAZINE 
• 6971-44-4 METHYLPYRIDIN-4-YLMETHYLAMINE 
• 129-17-9 Acid blue 1 
• 617-52-7 Dimethyl itaconate 
• 1937-37-7 Direct Black 38 
• 10034-88-5 Sodium bisulfate monohydrate 
• 59669-59-9 3-TERT-BUTYLISOXAZOL-5-AMINE 
• 25180-19-2 Direct Black BH 
• 81093-37-0 Pravastatin 
• 626-62-0 IODOCYCLOHEXANE 
• 86598-92-7 IMIBENCONAZOLE 
• 53250-83-2 2-Chloro-4-methylsulphonylbenzoic acid 
• 6032-2g-7 sec—Pentanol 
• 24521-76-4 4-HYDROXY-6-MERCAPTOPYRAZOLO[3,4-D]PYRIMIDINE 
• 8003-57-4 Direct Black 56 
• 575-03-1 7-HYDROXY-4-(TRIFLUOROMETHYL)COUMARIN 
• 17804-49-8 PROCION RED MX-5B 
• 28983-56-4 Acid Blue 93 
• 13767-89-0 GLAUBERITE 
• 922-32-7 Creatine phosphate disodium salt 
• 5413-75-2 Acid Red 73 
• 8008-31-9 Tangerine oil 
• 34801-09-7 2'-AMINOACETANILIDE 
• 2429-74-5 DIRECT BLUE 15 
• 110735-25-6 Direct Blue 151 
• 2105-59-1 2,4-Dichloro-5-fluoronitrobenzene 
• 629-82-3 DIOCTYL ETHER 

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