255833-41-1 Usage
Uses
Used in Pharmaceutical Industry:
Benzoic acid, 4-[[5-phenyl-4-(trifluoromethyl)-2-thiazolyl], is used as a pharmacological enhancer for the Orai1 Ca2+ Channel. Its application is aimed at fine-tuning the physiological properties of Orai1 in smooth and skeletal muscles. This enhancement can lead to improved understanding and potential treatments for various muscle-related conditions and disorders.
The compound's specific structure allows it to interact with the Orai1 channel, which plays a crucial role in calcium signaling pathways. By modulating the activity of this channel, the compound can potentially influence muscle contraction and other related processes. This makes it a valuable tool for researchers and pharmaceutical companies working on developing new therapies for muscle-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 255833-41-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,5,8,3 and 3 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 255833-41:
(8*2)+(7*5)+(6*5)+(5*8)+(4*3)+(3*3)+(2*4)+(1*1)=151
151 % 10 = 1
So 255833-41-1 is a valid CAS Registry Number.
255833-41-1Relevant academic research and scientific papers
Formation of thiazoles by reaction of 2-alkoxy-2-trifluoromethyl-3-phenyloxiranes with thioureas
Karavan,Nikiforov
, p. 741 - 745 (2007/10/03)
Reactions of 2-alkoxy-2-trifluoromethy-3-phenyloxiranes with N-arylthioureas involve α-opening of the oxirane ring with formation of 2-arylamino-4-trifluoromethyl-5-phenylthiazoles. Reactions of 2-alkoxy-2-trifluoromethyl-3-phenyloxiranes with N,N′-diphenylthiourea and N,N′-ethylenethiourea stop at the stage of formation of the corresponding hydroxytetrahydrothiazoles. The same products are formed by reactions of N,N′-diphenylthiourea and N,N′-ethylenethiourea with α-bromobenzyl trifluoromethyl ketone. The transformation of 2-alkoxyoxiranes into thiazoles is a new version of the Hantzsch synthesis.
