255837-23-1

Basic information

• Product Name: Methanesulfonic acid, trifluoro-, 3,4-dimethylphenyl ester
• CAS NO: 255837-23-1
• Molecular Formula: C9H9F3O3S
• Molecular Weight: 254.23
• Mol File: 255837-23-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Methanesulfonic acid, trifluoro-, 3,4-dimethylphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonic acid, trifluoro-, 3,4-dimethylphenyl ester(255837-23-1)
• EPA Substance Registry System: Methanesulfonic acid, trifluoro-, 3,4-dimethylphenyl ester(255837-23-1)

Safety Data

• Hazardous Substances Data: 255837-23-1(Hazardous Substances Data)

Upstream product

• 95-65-8 3,4-Dimethylphenol 
• 358-23-6 trifluoromethylsulfonic anhydride 

Downstream Products

• 72596-30-6 diethyl (3,4-dimethylphenyl)phosphonate 
• 38404-42-1 methyl 3,4-dimethylbenzoate 
• 21900-23-2 3,4-dimethylbenzoyl chloride 
• 3637-01-2 3,4-dimethylacetophenone 
• 255835-94-0 N-(3,4-dimethylphenyl)pyrrolidine 
• 56038-89-2 N-(1-ethylpropyl)-3,4-dimethyl-benzenamine 

Relevant articles and documents

Palladium-Catalyzed Chlorocarbonylation of Aryl (Pseudo)Halides Through In Situ Generation of Carbon Monoxide

An efficient palladium-catalyzed chlorocarbonylation of aryl (pseudo)halides that gives access to a wide range of carboxylic acid derivatives has been developed. The use of butyryl chloride as a combined CO and Cl source eludes the need for toxic, gaseous carbon monoxide, thus facilitating the synthesis of high-value products from readily available aryl (pseudo)halides. The combination of palladium(0), Xantphos, and an amine base is essential to promote this broadly applicable catalytic reaction. Overall, this reaction provides access to a great variety of carbonyl-containing products through in situ transformation of the generated aroyl chloride. Combined experimental and computational studies support a reaction mechanism involving in situ generation of CO.

Copper-Catalyzed Regioselective C-H Sulfonyloxylation of Electron-Rich Arenes with p-Toluenesulfonic Acid and Sulfonyloxylation of Aryl(mesityl)iodonium Sulfonates

Copper-catalyzed regioselective C-H sulfonyloxylation of electron-rich arenes with p-toluenesulfonic acid has been developed. Electron-rich benzene derivatives and heteroarenes can undergo this C-H sulfonyloxylation reaction to generate aryl tosylates. Furthermore, sulfonyloxylation of aryl(mesityl)iodonium sulfonates has also been investigated. Both aryl(mesityl)iodonium tosylates and triflates can react smoothly to get aryl sulfonates. The formed aryl sulfonates can be converted to phenols, as well as used as good partners of cross-coupling reactions.