2562-74-5Relevant academic research and scientific papers
Pharmacological and Toxicological Screening of Novel Benzimidazole-Morpholine Derivatives as Dual-Acting Inhibitors
Can, Nafiz nc,Evik, Ulviye Acar,Sagl?k, Beg m Nurpelin,Zkay, Yusuf,Atl?, Zlem,Baysal, Merve,Zkay, mide Demir,Can, zg r Devrim
, (2017/08/30)
The aim of this study was to investigate acetylcholinesterase (AChE), monoamine oxidase A (MAO-A), monoamine oxidase B (MAO-B), cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzyme inhibitory, and antimicrobial activities of a new series of 2-(4-s
A novel ionic liquid based on imidazolium cation as an efficient and reusable catalyst for the one-pot synthesis of benzoxazoles, benzthiazoles, benzimidazoles and 2-arylsubstituted benzimidazoles
Hasanpour, Maede,Eshghi, Hossein,Bakavoli, Mehdi,Mirzaeia, Mahdi
, p. 412 - 419 (2015/05/27)
A novel dicationic ionic liquid based on imidazolium cation is designed, synthesized and successfully used as catalyst for the one-pot synthesis of benzoxazoles, benzthiazoles, benzimidazoles and 2-arylsubstituted benzimidazoles. The remarkable feature of this new catalyst is its ethyleneoxy bridge which participates in dissolving organic compound in ionic liquid. The application of this ionic liquid is studied in a new one-pot method for synthesis of heterocyclic compounds under solvent-free conditions. Simple and convenient procedure, high conversion, reusability of catalyst, easy purification and shorter reaction time are the advantageous features of this method.
One-pot synthesis of benzimidazoles and benzothiazoles in the presence of Fe(HSO4)3 as a new and efficient oxidant
Eshghi, Hossein,Rahimizadeh, Mohammad,Shiri, Ali,Sedaghat, Parisa
experimental part, p. 515 - 518 (2012/04/23)
A series of substituted benzimidazoles and benzothiazoles were prepared through the one-pot reaction of ophenylenediamine and o-aminothiophenol with various aldehydes in the presence of ferric hydrogensulfate both in EtOH and water as solvent. The reactions proceed smoothly in excellent yield, high chemoselectivity and with an easy work-up.
