2562-84-7Relevant academic research and scientific papers
Benzimidazoles: A new class of carbonic anhydrase inhibitors
Khan, Khalid Mohammed,Khan, Momin,Saleem, Muhammad,Taha, Muhammad,Perveen, Shahnaz,Choudhary, Mohammad Iqbal
, p. 901 - 904 (2013/07/26)
Carbonic anhydrase inhibitory activity of benzimidazole derivatives 1-24 has been evaluated. Compounds 22 (IC50 = 7.47 ± 0.39 μM), 21 (IC50 = 10.31 ± 0.11 μM), 20 (IC50 = 23.1 ± 1.78 μM), 12 (IC50 = 12.16 ± 0.10
Conventional and microwave-assisted synthesis of benzimidazole derivatives and their in vitro inhibition of human cyclooxygenase
Secci, Daniela,Bolasco, Adriana,D'Ascenzio, Melissa,Della Sala, Flavio,Yanez, Matilde,Carradori, Simone
, p. 1187 - 1195 (2013/01/15)
A large series of 1,2-diaryl-benzimidazole and 2-aryl-1H-benzimidazole derivatives were synthesized with slight differences using both microwave irradiation and conventional heating methods. Usually higher yields and time reactions reduction were obtained
