2562-87-0Relevant academic research and scientific papers
Green syntheses of n-alkyl-2-styrylbenzimidazoles
Kumar, T. Ashok,Devi, B. Rama,Dubey
, p. 9569 - 9572 (2014/01/06)
Simple and green methodologies for the syntheses of 2-styrylbenzimidazoles (3a-c) and its N-alkyl derivatives (7a-i) have been developed. o-Phenylenediamine (1) was condensed with cinnamic acids (2a-c) resulting in 2-styrylbenzimidazoles (3a-c) using glycerol as a green and efficient solvent. 3 were also prepared alternatively by the condensation of 2-methylbenzimidazole (4) with benzaldehydes (5a-c) using glycerol as solvent. 2-Styrylbenzimidazoles (3a-c) and 2-methylbenzimidazole (4) were alkylated independently to obtain N-alkyl- 2-styrylbenzimidazole (7a-i) and N-alkyl-2-methylbenzimidazole (6a-c), respectively using DMS/DES/PhCH2Cl applying green methods such as simple physical grinding of reactants in solid phase, treating reactants in PEG-600 as a solvent in solution phase and using microwave irradiation of reactants respectively. Compounds 7a-i could also be prepared, alternatively, by heating 6a-c with 5a-c in glycerol at 180 °C for 3-4 h.
Microwave-assisted solvent-free synthesis of some styryl dyes with benzimidazole nucleus
Wang, Lanying,Zhang, Xiaogang,Li, Fengmei,Zhang, Zuxun
, p. 2245 - 2252 (2007/10/03)
A series of styryl dyes: 2-substituted styryl benzimidazole and α-methyl-2-substituted styryl benzimidazole were synthesized under solvent-free microwave irradiation by the condensation of 2-methylbenzimidazole or 2-ethylbenzimidazole with aromatic aldehydes in the presence of Ac 2O.
Application of Phase-Transfer Catalysis to the Synthesis of Mono- and Bis-stilbenes and Styryls
Lokhande, S. B.,Rangnekar, D. W.
, p. 485 - 488 (2007/10/02)
A novel and convenient method has been developed for the synthesis of substituted stilbenes by the condensation of active methyl group in suitably substituted toluenes with aromatic aldehydes in aq. medium at room temperature using benzyltriethylammonium chloride as a phase-transfer catalyst.This method has also been applied for the preparation of heterocyclic styryls and extended to the synthesis of bis-stilbenes and bis-styryls using aromatic dialdehydes in place of monoaldehydes.A comparison of the results shows that the present method is superior to the conventional methods in many respects.
