2562-90-5

Usage

Uses

Used in Biological and Medical Research:
4-[2-(1H-benzimidazol-2-yl)ethenyl]-N,N-dimethylaniline is used as a fluorescent dye for the visualization of specific cellular components and structures. Its ability to bind to DNA and RNA makes it useful for labeling nucleic acids in research applications.
Used in Labeling and Imaging Applications:
4-[2-(1H-benzimidazol-2-yl)ethenyl]-N,N-dimethylaniline is used as a labeling agent in biological samples due to its solubility in organic solvents, provided by the dimethylamine group on the aniline portion of the molecule. This makes it suitable for imaging applications in biological research.

Upstream product

• 20432-35-3 3-(4-dimethylamino-phenyl)-propenal 
• 95-54-5 1,2-diamino-benzene 
• 1552-96-1 p-dimethylaminocinnamic acid 
• 615-15-6 2-Methyl-1H-benzimidazole 
• 100-10-7 4-dimethylamino-benzaldehyde 

Relevant academic research and scientific papers

Intramolecular charge transfer emission of trans-2-[4′- (dimethylamino)styryl]benzimidazole: Effect of solvent and pH

The intramolecular charge transfer (ICT) exhibiting fluorophore trans-2-[4′-(dimethylamino)styryl]benzimidazole (t-DMASBI) is synthesized and its spectral characteristics are investigated using absorption and fluorescence techniques. The solvatochromic studies reveal that the molecule is emitting from the locally excited state in non-polar and from an ICT state in polar solvents. Photoisomerization competes with fluorescence, and in viscous solvents restriction on twisting of olefinic bond increases the fluorescence. Theoretical calculations predict that t-DMASBI exists in two confomeric forms. trans-B conformer is more stable than trans-A. The cis isomer also exists as two conformers. However, the relative stability of conformer B further increased in cis isomer. The spectral characteristics of both the conformers of trans isomer are nearly same. The longest wavelength transition of trans isomer has ππ* character and is due to HOMO-LUMO single excitation. The theoretical calculated excitation and emission energies of trans conformer differ very little from each other and are in excellent agreement with the absorption and fluorescence spectral maximum in cyclohexane. The prototropic study indicates that unlike other benzazole derivatives t-DMASBI forms only one kind of monocation upon protonation at benzimidazole nitrogen in water. But at lower pH the second protonation occurs at dimethylamino nitrogen to form dication.

A simple benzimidazole styryl-based colorimetric chemosensor for dual sensing application

A new colorimetric styryl-benzimidazole based receptor to recognize more than one analyte trans-2-[4′?(dimethylamino)styryl]benzimidazole) (L1) has been synthesized and fully characterized by 13C and 1H NMR, elemental analysis, UV–vi