25626-99-7Relevant academic research and scientific papers
Kinetics and mechanism of the anilinolysis of dimethyl and diethyl chloro(thiono)phosphates
Dey, Nilay Kumar,Hoque, Md. Ehtesham Ul,Kim, Chan Kyung,Lee, Bon-Su,Lee, Hai Whang
scheme or table, p. 544 - 548 (2009/04/04)
The deuterium kinetic isotope effects (KIEs) involving deuterated aniline nucleophiles (XC6H4ND2) are reported for the reactions of dimethyl chlorophosphate (1), dimethyl chlorothionophosphate (2), diethyl chlorophosphate
Phosphoric Amides. 5. Acid-Catalyzed Hydrolysis of Dimethyl N-(Alkylphenyl)phosphoramidates
Modro, Tomasz A.,Rijkmans, Bloys P.
, p. 3208 - 3211 (2007/10/02)
Studies of the acid-catalyzed hydrolysis of dimethyl N-(alkylphenyl)phosphoramidates demonstrate that the LFER between observed rates and basicities of the leaving amines is different for meta/para- and for ortho- substituted derivatives (slopes of logobsd vs. pKa are 0.4 and 0.9, respectively).Since the ΔS(excit) values and KSIE determined are approximately constant irrespective of the position of an alkyl group, the observed change in the slope of the rate/basicity plot is discussed in terms of the steric effects on solvation rather than as an indication of the change in reaction mechanism.
