25627-05-8

Basic information

• Product Name: dimethyl (4-methoxyphenyl)phosphoramidate
• CAS NO: 25627-05-8
• Molecular Formula: C₉H₁₄NO₄P
• Molecular Weight: 231.1855
• Mol File: 25627-05-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 298.9°C at 760 mmHg
• Flash Point: 134.6°C
• Density: 1.241g/cm³
• Vapor Pressure: 0.00123mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: dimethyl (4-methoxyphenyl)phosphoramidate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl (4-methoxyphenyl)phosphoramidate(25627-05-8)
• EPA Substance Registry System: dimethyl (4-methoxyphenyl)phosphoramidate(25627-05-8)

Safety Data

• Hazardous Substances Data: 25627-05-8(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 813-77-4 Dimethyl chlorophosphate 
• 7006-87-3 (4-Methoxy-phenyl)-imidophosphorsaeure-trimethylester 
• 100-17-4 para-methoxynitrobenzene 
• 121-45-9 phosphorous acid trimethyl ester 
• 7007-02-5 dimethyl N-(4-methoxyphenyl)-N-methylphosphoramidate 
• 96-36-6 methyl phosphite 

Relevant articles and documents

Structural Effects in Amides. Crystal and Molecular Structures of Phosphoric and Carboxylic Anilides

Crystal and molecular structures of three N-aryl carboxylic amides (RCONHAr) and three dimethyl N-arylphosphoramidates (MeO)2P(O)NHAr were determined and are discussed together with those of related systems described in the literature.Carboxylic amides exist in the trans configuration of the CO and NH groups, and both the N-aryl and C-aryl (for R = Ar) rings are considerably twisted with respect to the amide plane.Phosphoramidates prefer the cis orientation of the PO and NH groups, with the N-aryl group bisecting the MeO-P-OMe angle.Substituents in the N-aryl group have a weak effect on structural parameters of both amide functions.For the phosphoramidates a linear free-energy relationship between the intramolecular P=O...H-N hydrogen bonding and the acidity of the ArNH3+ ions has been obtained.

Kinetics and mechanism of the anilinolysis of dimethyl and diethyl chloro(thiono)phosphates

The deuterium kinetic isotope effects (KIEs) involving deuterated aniline nucleophiles (XC6H4ND2) are reported for the reactions of dimethyl chlorophosphate (1), dimethyl chlorothionophosphate (2), diethyl chlorophosphate