256342-26-4

Basic information

• Product Name: (2R,3R,4S,5S,6S)-4-Benzyloxy-6-((2S,3R,4R,5S)-4,5-bis-allyloxy-3-benzyloxy-tetrahydro-pyran-2-yloxy)-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-ol
• Synonyms: (2R,3R,4S,5S,6S)-4-Benzyloxy-6-((2S,3R,4R,5S)-4,5-bis-allyloxy-3-benzyloxy-tetrahydro-pyran-2-yloxy)-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-ol
• CAS NO: 256342-26-4
• Molecular Weight: 600.706
• Mol File: 256342-26-4.mol

Chemical Properties

• CAS DataBase Reference: (2R,3R,4S,5S,6S)-4-Benzyloxy-6-((2S,3R,4R,5S)-4,5-bis-allyloxy-3-benzyloxy-tetrahydro-pyran-2-yloxy)-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4S,5S,6S)-4-Benzyloxy-6-((2S,3R,4R,5S)-4,5-bis-allyloxy-3-benzyloxy-tetrahydro-pyran-2-yloxy)-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-ol(256342-26-4)
• EPA Substance Registry System: (2R,3R,4S,5S,6S)-4-Benzyloxy-6-((2S,3R,4R,5S)-4,5-bis-allyloxy-3-benzyloxy-tetrahydro-pyran-2-yloxy)-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-ol(256342-26-4)

Safety Data

• Hazardous Substances Data: 256342-26-4(Hazardous Substances Data)

Upstream product

• 126092-08-8 phenyl 2,3-di-O-isopropylidene-1-thio-α-D-mannopyranoside 
• 256341-91-0 (2R,3S,4R,5S,6R)-5-(4-Methoxy-benzyloxy)-6-methoxymethyl-2-phenylsulfanyl-tetrahydro-pyran-3,4-diol 
• 256342-23-1 tert-Butyl-[(3aS,4R,6R,7R,7aS)-7-(4-methoxy-benzyloxy)-2,2-dimethyl-4-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-6-ylmethoxy]-dimethyl-silane 
• 306726-10-3 (1R,2S,3S)-2,3-Bis-allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-1-thiazol-2-yl-butan-1-ol 
• 306726-12-5 Benzoic acid (1R,2R,3S)-2,3-bis-allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-1-thiazol-2-yl-butyl ester 
• 65973-56-0 (S,S)-2,3-bis-allyloxy-butane-1,4-diol 
• 256342-25-3 Benzoic acid (2S,3R,4R,5S)-4,5-bis-allyloxy-2-[(2S,3S,4S,5R,6R)-4-benzyloxy-3-methoxy-5-(4-methoxy-benzyloxy)-6-methoxymethyl-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3-yl ester 
• 256342-02-6 Benzoic acid (2S,3R,4R,5S)-4,5-bis-allyloxy-2-[(2S,3S,4R,5R,6R)-4-benzyloxy-3-hydroxy-5-(4-methoxy-benzyloxy)-6-methoxymethyl-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3-yl ester 
• 256342-03-7 (2S,3R,4S,5S)-4,5-Bis-allyloxy-2-[(2S,3S,4S,5R,6R)-4-benzyloxy-3-methoxy-5-(4-methoxy-benzyloxy)-6-methoxymethyl-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3-ol 
• 256341-92-1 (2R,3S,4R,5R,6R)-4-Benzyloxy-5-(4-methoxy-benzyloxy)-6-methoxymethyl-2-phenylsulfanyl-tetrahydro-pyran-3-ol 
• 256341-87-4 Benzoic acid (3R,4R,5S)-4,5-bis-allyloxy-2-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-3-yl ester 
• 256341-90-9 (3aS,4R,6R,7R,7aS)-7-(4-Methoxy-benzyloxy)-6-methoxymethyl-2,2-dimethyl-4-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran 
• 256341-93-2 (2R,3S,4R,5R,6R)-4-Benzyloxy-5-(4-methoxy-benzyloxy)-6-methoxymethyl-tetrahydro-pyran-2,3-diol 
• 256341-89-6 [(3aS,4R,6R,7R,7aS)-7-(4-Methoxy-benzyloxy)-2,2-dimethyl-4-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-6-yl]-methanol 

Downstream Products

• 256341-85-2 (3S,4R,5R,6S)-5-Benzyloxy-6-((2S,3S,4R,5R,6R)-4-benzyloxy-3-methoxy-6-methoxymethyl-5-triisopropylsilanyloxy-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3,4-diol 
• 256342-29-7 Chloro-acetic acid (3S,4R,5R,6S)-5-benzyloxy-6-((2S,3S,4R,5R,6R)-4-benzyloxy-3-methoxy-6-methoxymethyl-5-triisopropylsilanyloxy-tetrahydro-pyran-2-yloxy)-4-hydroxy-tetrahydro-pyran-3-yl ester 
• 256342-06-0 Chloro-acetic acid (2S,3R,4R,5S)-3-benzyloxy-2-((2S,3S,4R,5R,6R)-4-benzyloxy-3-methoxy-6-methoxymethyl-5-triisopropylsilanyloxy-tetrahydro-pyran-2-yloxy)-5-hydroxy-tetrahydro-pyran-4-yl ester 
• 256342-13-9 C₄₀H₄₈O₁₃ 
• 256342-31-1 Benzoic acid (2S,3R,4R,5S)-3-benzyloxy-2-((2S,3S,4R,5R,6R)-4-benzyloxy-3-methoxy-6-methoxymethyl-5-triisopropylsilanyloxy-tetrahydro-pyran-2-yloxy)-5-hydroxy-tetrahydro-pyran-4-yl ester 
• 256342-21-9 C₃₉H₅₆O₁₄Si 
• 256342-30-0 Benzoic acid (2S,3R,4R,5S)-3-benzyloxy-2-((2S,3S,4R,5R,6R)-4-benzyloxy-3-methoxy-6-methoxymethyl-5-triisopropylsilanyloxy-tetrahydro-pyran-2-yloxy)-5-(2-chloro-acetoxy)-tetrahydro-pyran-4-yl ester 
• 256342-14-0 C₄₆H₆₂O₁₃Si 
• 256342-12-8 C₄₇H₅₂O₁₄ 
• 256342-27-5 C₄₇H₅₄O₁₅ 
• 256342-10-6 C₄₆H₆₄O₁₄Si 
• 256342-19-5 C₄₇H₆₄O₁₅Si 
• 256342-18-4 C₄₆H₆₄O₁₅Si 
• 256342-15-1 C₄₆H₆₄O₁₅Si 

Relevant articles and documents

Total synthesis of everninomicin 13,384-1 - Part 2: Synthesis of the FGHA2 fragment

The stereoselective synthesis of everninomicin's 13,384-1 (1) FGHA2 fragment (2) in a suitable form for incorporation into the final target (1) is described. The construction of the FG 1,1′-disaccharide linkage relied on a new method based on tin-acetal chemistry, while for the GH orthoester bridge, a number of approaches were explored. Final success for the latter construction came when a novel 1,2-phenylseleno migration reaction was applied to couple rings G and H, followed by ketene acetal and orthoester formation.