306726-09-0

Basic information

• Product Name: (2S,3S)-2,3-Bis-allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-butan-1-ol
• Synonyms: (2S,3S)-2,3-Bis-allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-butan-1-ol
• CAS NO: 306726-09-0
• Molecular Weight: 440.655
• Mol File: 306726-09-0.mol

Chemical Properties

• CAS DataBase Reference: (2S,3S)-2,3-Bis-allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-butan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-2,3-Bis-allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-butan-1-ol(306726-09-0)
• EPA Substance Registry System: (2S,3S)-2,3-Bis-allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-butan-1-ol(306726-09-0)

Safety Data

• Hazardous Substances Data: 306726-09-0(Hazardous Substances Data)

Upstream product

• 65973-56-0 (S,S)-2,3-bis-allyloxy-butane-1,4-diol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 65973-54-8 (2R,3R)-2,3-Bis-allyloxy-succinic acid diethyl ester 

Downstream Products

• 256342-25-3 Benzoic acid (2S,3R,4R,5S)-4,5-bis-allyloxy-2-[(2S,3S,4S,5R,6R)-4-benzyloxy-3-methoxy-5-(4-methoxy-benzyloxy)-6-methoxymethyl-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3-yl ester 
• 256342-02-6 Benzoic acid (2S,3R,4R,5S)-4,5-bis-allyloxy-2-[(2S,3S,4R,5R,6R)-4-benzyloxy-3-hydroxy-5-(4-methoxy-benzyloxy)-6-methoxymethyl-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3-yl ester 
• 256342-05-9 [(2R,3R,4R,5S,6S)-4-Benzyloxy-6-((2S,3R,4R,5S)-4,5-bis-allyloxy-3-benzyloxy-tetrahydro-pyran-2-yloxy)-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-yloxy]-triisopropyl-silane 
• 256342-04-8 (2S,3S,4S,5R,6R)-4-Benzyloxy-2-((2S,3R,4R,5S)-4,5-bis-allyloxy-3-benzyloxy-tetrahydro-pyran-2-yloxy)-3-methoxy-5-(4-methoxy-benzyloxy)-6-methoxymethyl-tetrahydro-pyran 
• 256342-03-7 (2S,3R,4S,5S)-4,5-Bis-allyloxy-2-[(2S,3S,4S,5R,6R)-4-benzyloxy-3-methoxy-5-(4-methoxy-benzyloxy)-6-methoxymethyl-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3-ol 
• 256342-26-4 (2R,3R,4S,5S,6S)-4-Benzyloxy-6-((2S,3R,4R,5S)-4,5-bis-allyloxy-3-benzyloxy-tetrahydro-pyran-2-yloxy)-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-ol 
• 306726-12-5 Benzoic acid (1R,2R,3S)-2,3-bis-allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-1-thiazol-2-yl-butyl ester 
• 306726-10-3 (1R,2S,3S)-2,3-Bis-allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-1-thiazol-2-yl-butan-1-ol 
• 306726-48-7 (1S,2S,3S)-2,3-Bis-allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-1-thiazol-2-yl-butan-1-ol 
• 256341-87-4 Benzoic acid (3R,4R,5S)-4,5-bis-allyloxy-2-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-3-yl ester 

Relevant articles and documents

Total synthesis of everninomicin 13,384-1 - Part 2: Synthesis of the FGHA2 fragment

The stereoselective synthesis of everninomicin's 13,384-1 (1) FGHA2 fragment (2) in a suitable form for incorporation into the final target (1) is described. The construction of the FG 1,1′-disaccharide linkage relied on a new method based on tin-acetal chemistry, while for the GH orthoester bridge, a number of approaches were explored. Final success for the latter construction came when a novel 1,2-phenylseleno migration reaction was applied to couple rings G and H, followed by ketene acetal and orthoester formation.