25636-49-1

Basic information

• Product Name: 3,3-diMethoxypentane
• Synonyms: 3,3-diMethoxypentane
• CAS NO: 25636-49-1
• Molecular Formula: C₇H₁₆O₂
• Molecular Weight: 132.20074
• Mol File: 25636-49-1.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 59 °C(Press: 63 Torr)
• Appearance: /
• Density: 0.863 g/cm3(Temp: 25 °C)
• CAS DataBase Reference: 3,3-diMethoxypentane(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-diMethoxypentane(25636-49-1)
• EPA Substance Registry System: 3,3-diMethoxypentane(25636-49-1)

Safety Data

• Hazardous Substances Data: 25636-49-1(Hazardous Substances Data)

Usage

General Description

3,3-diMethoxypentane, also known as DMP, is a chemical compound with the molecular formula C7H16O2. It is a clear, colorless liquid that is commonly used as a solvent in various industrial applications. DMP is known for its low toxicity and low evaporation rate, making it a suitable option for use in various chemical processes. It is also used as a component in the manufacturing of fragrances and flavors. DMP is flammable and should be handled with caution to prevent potential hazards. Overall, 3,3-diMethoxypentane is a versatile chemical with a range of uses in different industries.

Upstream product

• 96-22-0 pentan-3-one 
• 149-73-5 trimethyl orthoformate 
• 1445-45-0 Trimethyl orthoacetate 
• 67-56-1 methanol 

Downstream Products

• 143157-29-3 (4R,5R)-4-[(R)-((R)-2,2-Diethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-2,2-diethyl-[1,3]dioxan-5-ol 
• 120157-59-7 1,2:5,6-di-O-(3-pentylidene)-D-mannitol 
• 156696-20-7 (2S,3S)-2-(4-methoxybenzyloxy)-3,4-O-(3-pentylidene)-1,3,4-butanetriol 
• 36839-67-5 3-methoxypentane 
• 616-38-6 carbonic acid dimethyl ester 
• 152386-85-1 (1R,2S)-1-((R)-2,2-diethyl-1,3-dioxolan-4-yl)-2-((4-methoxybenzyl)oxy)ethan-1-ol 
• 28791-86-8 3,3-di(1-pyrazolyl)pentane 
• 515870-46-9 (4R,5R)-2,2-Diethyl-[1,3]dioxolane-4,5-dicarboxylic acid diamide 
• 915708-06-4 2-(2,2-diethyl-4-methyl-[1,3]dioxolan-4-yl)-5-(4-methoxy-benzyloxymethyl)-hex-5-en-1-ol 
• 164215-26-3 (R)-2-Benzyloxy-2-((R)-2,2-diethyl-[1,3]dioxolan-4-yl)-N,N-dimethyl-acetamide 
• 164215-29-6 (S)-2-[(R)-Benzyloxy-((R)-2,2-diethyl-[1,3]dioxolan-4-yl)-methyl]-but-3-yne-1,2-diol 
• 171189-77-8 (R)-1-Benzyloxy-1-((R)-2,2-diethyl-[1,3]dioxolan-4-yl)-3-ethoxy-but-3-en-2-one 
• 171189-78-9 (S)-2-[(R)-Benzyloxy-((R)-2,2-diethyl-[1,3]dioxolan-4-yl)-methyl]-4-trimethylsilanyl-but-3-yne-1,2-diol 
• 164215-27-4 (R)-3-[(R)-Benzyloxy-((R)-2,2-diethyl-[1,3]dioxolan-4-yl)-methyl]-2-ethoxy-5-trimethylsilanyl-pent-1-en-4-yn-3-ol 

Relevant articles and documents

Methyl homologues of methyl jasmonate and methyl dihydrojasmonate (Hedione) from sorbyl alcohol

Treatment of cycloalkanone dimethyl acetals 3-6 with sorbyl alcohol (=(2E,4E)-hexa-2,4-dien-1-ol; 1) in the presence of acids afforded the novel cycloalkenones 8, 9, 11, and 13 via a domino reaction (Claisen rearrangement with intramolecular ene reaction and retro-ene reaction). Cyclopentenone 8 was readily transformed into 14 and 15, methyl homologues of racemic methyl jasmonate (16) and methyl dihydrojasmonate (= Hedione; 17), respectively. The organoleptic properties of 14 and 15 are also discussed.

Ecofriendly fast batch synthesis of dioxolanes, dithiolanes, and oxathiolanes without solvent under microwave irradiation

2,2-Dimethoxypropane and 3,3-dimethoxypentane react with 1,2-ethanediol, thio, and oxathio analogues to give the corresponding protected carbonyls in high yield under mild solvent-free conditions. These environmentally benign conditions under microwave irradiation are applied to a large-scale synthesis.

Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles

Inhibition of the MDM2-p53 protein-protein interaction is being actively pursued as a new anticancer therapeutic strategy, and spiro-oxindoles have been designed as a class of potent and efficacious small-molecule inhibitors of this interaction (MDM2 inhibitors). Our previous study showed that some of our first-generation spiro-oxindoles undergo a reversible ring-opening-cyclization reaction that, from a single compound in protic solution, results in an equilibrium mixture of four diastereoisomers. By exploiting the ring-opening-cyclization reaction mechanism, we have designed and synthesized a series of second-generation spiro-oxindoles with symmetrical pyrrolidine C2 substitution. These compounds undergo a rapid and irreversible conversion to a single, stable diastereoisomer. Our study has yielded compound 31 (MI-1061), which binds to MDM2 with Ki = 0.16 nM, shows excellent chemical stability, and achieves tumor regression in the SJSA-1 xenograft tumor model in mice.

4-chloro-3,5-dimethyl-2-sulfonyl pyridines

2-Sulfonylpyridine derivatives can be industrially produced efficiently by reacting a sulfonyl cyanide derivative with an α,β-unsaturated carbonyl compound and a 2-{[(2-pyridyl)methyl]thio}-1H-benzimidazole skeleton can be formed in one step in a good yield by reacting this type of the 2-sulfonylpyridine derivative with a 2-methylthio-1H-benzimidazole derivative in the presence of an organolithium compound.