256388-25-7Relevant academic research and scientific papers
Synthesis of 4-(2-diphenylphosphino-1-naphthyl)-2-phenylquinazoline; A potential P-N chelating ligand for asymmetric catalysis
Gautheron Chapoulaud,Audoux,Ple,Turck,Queguiner
, p. 9005 - 9007 (1999)
We describe a multistep synthesis leading in a good yield to the title compound. The biaryl linkage was formed in a Pd-catalysed coupling of 2-phenyl-4-chloroquinazoline with 2-methoxy-1-naphthylboronic acid. A further metal-catalysed reaction gave the formation of the naphthylphosphorus bond allowing us to obtain the required phosphonimine ligand 1 as the racemate.
