256441-01-7

Upstream product

• 5524-05-0 (2R,5R)-5-isopropenyl-2-methylcyclohexanone 
• 256440-99-0 (1R,3R,6R)-3-[1-(chloromethyl)ethenyl]-2-[(E)-3-(4-methoxyphenylmethoxy)propylidene]-1-(methoxymethoxy)-6-methylcyclohexane propanol 
• 256440-98-9 (1R,3R,6R)-1-allyl-3-[1-(chloromethyl)ethenyl]-2-[(E)-3-(4-methoxyphenylmethoxy)propylidene]-1-(methoxymethoxy)-6-methylcyclohexane 
• 256440-97-8 (1R,3R,6R)-1-allyl-3-[1-(chloromethyl)ethenyl]-2-[(E)-3-(4-methoxyphenylmethoxy)propylidene]-6-methyl-1-cyclohexanol 
• 256440-95-6 (2R,3R,6R)-3-[1-(chloromethyl)ethenyl]-2-[(R)-1-hydroxy-3-(4-methoxyphenylmethoxy)propyl]-6-methylcyclohexanone 
• 256440-96-7 (3R,6R)-3-[1-(chloromethyl)ethenyl]-2-[(E)-3-(4-methoxtphenylmethoxy)propylidene]-6-methylcyclohexanone 
• 187665-47-0 (2R,5R)-5-(1-chloromethylethenyl)-2-methylcyclohexanone 
• 123-11-5 4-methoxy-benzaldehyde 
• 128461-65-4 3-(p-methoxybenzyloxy)propanal 
• 256441-00-6 (1R,3R,6R)-3-[1-(chloromethyl)ethenyl]-2-[(E)-3-(4-methoxyphenylmethoxy)propylidene]-1-(methoxymethoxy)-6-methylcyclohexane propanal 

Relevant academic research and scientific papers

Efficient construction of 8-membered ring framework of vinigrol through SmI2-induced coupling cyclization

The 8-membered ring framework of vinigrol, a unique tricyclic diterpene isolated as a novel antihypertensive compound from a culture of Virgaria nigra, was efficiently synthesized employing an SmI2-induced intramolecular coupling. It is particularly noteworthy that the 8-membered carbocycle was cyclized in quantitative yields under non-high-dilution conditions.