256451-15-7Relevant academic research and scientific papers
Pyrrolidinones derived from (S)-pyroglutamic acid. Part 4. α, β-diaminopyrrolidinones
Chan, Philip W.H.,Cottrell, Ian F.,Moloney, Mark G.
, p. 3007 - 3012 (2001)
The electrophilic amination of a β-aminolactam to provide direct acess to conformationally constrained diamines was discussed. The β-aminolactams was found to be derived from the conjugate addition of O,N-dibenzylhydroxylamine to a highly activated α,β-un
Azasugar analogues: Conformationally restricted vicinal diamine derived from (S)-(-)-pyroglutamic acid
Chan, Philip W. H.,Cottrell, Ian F.,Moloney, Mark G.
, p. 3887 - 3891 (2007/10/03)
The preparation of a diamino substituted pyrrolidinone system in a diastereoselectively controlled manner is described. The procedure employed made use of electrophilic amination of a chiral bicyclic γ-lactam, which when subjected to sequential deprotecti
