256469-26-8Relevant articles and documents
Studies directed toward the synthesis of taxanes: Evaluation of the B- ring formation by an intramolecular nitrile oxide cycloaddition
Nivlet, Alex,Dechoux, Luc,Martel, Jean-Philippe,Proess, Gottfried,Mannes, Dietrich,Alcaraz, Lilian,Harnett, Jerry J.,Le Gall, Thierry,Mioskowski, Charles
, p. 3241 - 3249 (1999)
Several models for the formation of the 8-membered B-ring of taxanes by an intramolecular nitrile oxide [3+2] cycloaddition were prepared from the monoacetal of 2,2-dimethylcyclohexane-1,3-dione (5). The nitrile oxides were then generated under high-dilut