256477-73-3

Basic information

• Product Name: ethyl trans-4-{[(1,4-dichloro-7-isoquinolinyl)sulphonyl]amino}cyclohexanecarboxylate
• Synonyms: ethyl trans-4-{[(1,4-dichloro-7-isoquinolinyl)sulphonyl]amino}cyclohexanecarboxylate
• CAS NO: 256477-73-3
• Molecular Weight: 431.34
• Mol File: 256477-73-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl trans-4-{[(1,4-dichloro-7-isoquinolinyl)sulphonyl]amino}cyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl trans-4-{[(1,4-dichloro-7-isoquinolinyl)sulphonyl]amino}cyclohexanecarboxylate(256477-73-3)
• EPA Substance Registry System: ethyl trans-4-{[(1,4-dichloro-7-isoquinolinyl)sulphonyl]amino}cyclohexanecarboxylate(256477-73-3)

Safety Data

• Hazardous Substances Data: 256477-73-3(Hazardous Substances Data)

Upstream product

• 223671-80-5 1,4-dichloro-7-isoquinolinesulphonyl chloride 
• 1678-68-8 ethyl trans-4-aminocyclohexanecarboxylate 
• 223671-81-6 4-chloro-1-oxo-1,2-dihydro-7-isoquinolinesulfonyl chloride 
• 56241-09-9 4-chloro-1-(2H)-isoquinolone 
• 491-30-5 1-isoquinolone 

Downstream Products

• 256478-59-8 ethyl trans-4-{[(4-chloro-1-guanidino-7-isoquinolinyl)sulphonyl]amino}cyclohexane-carboxylate 

Relevant articles and documents

Composition for the treatment of damaged tissue

A pharmaceutical for use in damaged tissue, such as wound, treatment (e.g. healing) is described. The pharmaceutical comprising a composition which comprises: (a) a growth factor; and (b) an inhibitor agent; and optionally (c) a pharmaceutically acceptable carrier, diluent or excipient; wherein the inhibitor agent can inhibit the action of at least one specific adverse protein (e.g. a specific protease) that is upregulated in a damaged tissue, such as a wound, environment.

Isoquinolines

Isoquinolinylguanidine compounds of formula (I): STR1 wherein the substituents are as defined herein, and salts thereof, are disclosed as urokinase inhibitors.